Sökning: "Ola Johansson"
Visar resultat 6 - 10 av 22 avhandlingar innehållade orden Ola Johansson.
6. Design and synthesis of inhibitors that target the serine protease thrombin, the malarial aspartyl proteases plasmepsin I and II, and the hepatitis C virus NS3 serine protease
Sammanfattning : This thesis addresses the design, synthesis, and structure-activity relationships of protease inhibitors that target the serine protease thrombin, the malarial aspartic proteases plasmepsin I and II, and the hepatitis C virus (HCV) NS3 serine protease. Furthermore, the backgrounds of each of the three types of diseases in question are discussed in detail, and consideration is given as to why it is assumed that inhibition of the mentioned proteases will help prevent or cure cardiovascular diseases, malaria, and hepatitis C. LÄS MER
7. The Conditions of Peasant Organisation : Fragmented Livelihoods and Social Memory in post-Independent Mozambique
Sammanfattning : The thesis is an inquiry into peasants’ collective organisation inMozambique since the country’s Independence in 1975. It brings togetherfour published studies and aims to understand the historical and socioeconomic conditions for different forms of peasant organisation in postIndependence Mozambique. LÄS MER
8. Proteomic strategies for blood biomarker development in rare dystrophinopathies
Sammanfattning : Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are two rare genetic disorders of the family dystrophinopathy. They are both caused by the lack of, or reduced production of, the protein dystrophin. LÄS MER
9. Role of Islet Endothelial Cells in β-cell Function and Growth
Sammanfattning : The pancreatic islets are collections of endocrine cells, dispersed throughout the pancreas. In adult islets, endocrine cells are closely associated with capillary endothelial cells and receive a high blood perfusion. Transplanted pancreatic islets, on the other hand, have a vascular disturbance, manifested as decreased blood vessel density. LÄS MER
10. Displaced Femoral Neck Fractures : A prospective randomized study of clinical outcome, nutrition and costs
Sammanfattning : Displaced femoral neck fractures comprise more than a third of all hip fractures. There is controversy as to the optimal treatment. Despite attempts to improve the methods for internal fixation, complication rates have been almost unchanged: 20-40% non-union and late segmental collapse in another 10-20%. LÄS MER
