Sökning: "Odyssey"

Visar resultat 6 - 10 av 12 avhandlingar innehållade ordet Odyssey.

  1. 6. From Photons to Worlds: An odyssey in exoplanet detection and characterisation

    Författare :Iskra Georgieva; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Since the first unambiguous detection of a planet around a Sun-like, the interest in the new and exciting field of exoplanets has grown immensely. New and exciting developments are seen at a pace unparalleled for most subfields of astronomy and astrophysics. LÄS MER

  3. 7. WNT/FZD signaling : an odyssey from molecular pharmacology to brain (patho)physiology

    Författare :Jacomijn P Dijksterhuis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The 19 members of the lipoglycoprotein family of WNTs interact with the highly conserved cysteine-rich domain (CRD) of ten members of the Frizzled (FZD1-10) family. The seven transmembrane-spanning surface receptors are listed as G protein-coupled receptors and are known to interact with heterotrimeric G proteins as well as the scaffolding protein disheveled. LÄS MER

  4. 8. An Organic Chemistry Odyssey : Imaging Mass Spectrometry in Neurotherapeutics, Asymmetric Methodology Development and Natural Product Synthesis

    Författare :Marvin Villacrez; Kemisk biologi med inriktning mot läkemedelsutveckling; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Masspektrometri; totalsyntes; avbildande massspektrometri; MALDI avbildande massspektrometri; asymmetrisk syntes; farmakokinetik; dynamisk kinetisk resolution; Aasymetrisk överföringshydrogenering; klozapin; Läkemedelsmetabolism; läkemedelsdistribution; aminoalkoholer; Aspidophylline A; mass spectromery; Imaging mass spectrometry; Total synthesis; Dynamic kinetic resolution; asymmetric transfer hydrogenation; Aspidophylline A; Drug distribution; Drug metabolism; Drug Metabolism and Mass Spectrometry Imaging; MALDI mass spectrometry imaging; clozapine; amino alcohols; pharmacokinetics;

    Sammanfattning : The development of imaging technologies and brain models is crucial for advancements in neurotherapeutic drug discovery and development. They assume a critical role in evaluating essential parameters such as drug blood-brain barrier (BBB) permeation, distribution, and metabolism, all of which are vital for the development of safe and effective medications. LÄS MER

  5. 9. The odyssey of MYC transcript from the nucleus to the cytoplasm : the molecular mechanism of the gene gating in human cancer cells

    Författare :Mirco Martino; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Pathological expression of the MYC oncogene is a common denominator in a wide range of cancers and is linked with abnormal cell proliferation. To achieve this status, the MYC gene benefits from being embedded in a region rich in enhancers and super-enhancers that are often absent in the normal cell counterparts. LÄS MER

  7. 10. En himmel av sten : Willy Kyrklund och det grekiska

    Författare :Thomas Sjösvärd; Björn Sundberg; Roland Lysell; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Willy Kyrklund; antiquity; philology; myth; literary geography; hermeneutics; Adorno; Literature; Litteraturvetenskap;

    Sammanfattning : The aim of this dissertation is to investigate the notion of the ‘Greek’ in the work of Willy Kyrklund [1921–2009].Kyrklund authorship can be interpreted as a dialogue with the mythology and literature of ancient Greece. LÄS MER