Sökning: "NKT"

Visar resultat 21 - 25 av 40 avhandlingar innehållade ordet NKT.

  1. 21. Immunoregulation in an experimental model of allergic asthma

    Författare :Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

    Sammanfattning : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. LÄS MER

  3. 22. Effect of quinoline-3-carboxamides on myeloid cells in inflammation and cancer

    Författare :Adnan Deronic; Immunologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Quinoline-3-carboxamide; myeloid cell; inflammation; cancer; peritonitis; mammary carcinoma; fibrosis;

    Sammanfattning : The quinoline-3-carboxamides (Q compounds) are a family of small molecules that ameliorate various types of murine inflammatory autoimmune disease. One such compound has also demonstrated anti-tumor effects in murine tumor models. LÄS MER

  4. 23. HIV-1/HCV co-infection : immunity and viral dynamics

    Författare :Karolin Falconer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) are the agents behind two viral epidemics causing huge morbidity and mortality worldwide. HCV infection is a leading cause of end-stage liver disease. LÄS MER

  5. 24. Exosomes : the future of vaccination?

    Författare :Ulf Gehrmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are small membrane vesicles that are secreted by cells as means of intercellular communication. They are typically between 50 and 100 nm in diameter and originate from the endosomal compartment of cells. Exosomes have been considered a potential novel cell- free therapeutic agent since exosomes are capable of antigen presentation. LÄS MER

  7. 25. Exosomes : immunomodulators in cancer and therapy

    Författare :Stefanie Hiltbrunner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Exosomes are nano-sized membrane vesicles derived from the late endosomal compartment. They are capable of transferring proteins, lipids and RNA between cells. B cell and dendritic cell (DC)-derived exosomes express major histocompatibility complex (MHC) class I and II, as well as costimulatory molecules (CD80/86) and can initiate T cell responses. LÄS MER