Sökning: "NKT"

Visar resultat 11 - 15 av 40 avhandlingar innehållade ordet NKT.

  1. 11. Modulation of invariant NKT cell activity by cytokines and receptors in human disease

    Författare :Carlotta Kuylenstierna; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Invariant natural killer T (NKT) cells are innate-like lymphocytes with both immunoregulatory and cytotoxic functions that play a role as activators and regulators of the immune response in many diseases. NKT cells are believed to bridge the innate and adaptive immune systems by rapidly producing large quantities of cytokines after recognition of CD1d-presented lipid antigens. LÄS MER

  3. 12. The therapeutic potential of ex vivo expanded natural killer (NK) cells for immunotherapy of cancer

    Författare :Hayrettin Guven; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Natural killer NK cells; Natural killer-like T NKT cells; Gene transfer; Retrovirus; Good manufacturing practice GMP ; Ex vivo; In vivo; SCID-beige.;

    Sammanfattning : Cell and gene therapy of cancers has received much attention in the past decade. A number of applications of cancer treatment have been developed and used. One of the recent applications is immunotherapy of tumours with human natural killer (NK) cells. LÄS MER

  4. 13. Innate and adaptive cellular immunity in chronic HCV and HIV-1 infection

    Författare :Veronica D Gonzalez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HCV; HIV-1; co-infection; adaptive immunity; innate immunity; NK cell; NKT cell; CD4 T cell; CD8 T cell; IFNalpha; ribavirin; immune activation;

    Sammanfattning : Viral infections are initially countered by an innate immune response as a first line of defence followed by an adaptive immune response. However, certain viruses successfully evade cellular immune responses and establish chronic infection. LÄS MER

  5. 14. Genetics and functions of innate-like lymphocyte subsets

    Författare :Julia Rolf; Göteborgs universitet; []
    Nyckelord :innate-like lymphocyte; CD1d; autoimmunity; genetic mapping; microarray; Salmonella infection;

    Sammanfattning : The immune system contains three different branches: innate immunity, adaptive immunity and innate-like lymphocytes that share properties both with the innate and adaptive immune cells. The innate-like lymphocytes have the capacity to rapidly become activated by invading pathogens and also to modulate immune responses and thereby inhibit or promote inflammation. LÄS MER

  7. 15. Innate mechanisms regulating B cell activation in inflammatory diseases

    Författare :Sara Lind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Generation of powerful and highly specific immune responses against invading pathogens is essential to our survival. However, the immune system can cause disease if activated in an inappropriate manner. LÄS MER