Sökning: "Marja Jäättelä"

Hittade 2 avhandlingar innehållade orden Marja Jäättelä.

1. 1. Anti-Apoptotic Proteins in Nerve Cell Survival and Neurodegeneration

   Författare :Laura Korhonen; Marja Jäättelä; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; neuronal cell death; XIAP; RIAP-2; Hippocalcin; Bcl-2; Bcl-X; kainic acid; DRG; estrogen; Neurovetenskap; Neurology; Neurologi; Developmental Neurosciences; medicinsk utvecklings- och neurobiologi;

   Sammanfattning : Apoptosis is a genetically regulated cell death program, which shows distinct morphological characteristics. It takes place during neuronal development and in some neurodegenerative diseases. During apoptosis, the intracellular proteins are degraded by various caspases, cysteine aspartases, which are regulated by pro- and anti-apoptotic signals. LÄS MER

3. 2. Cathepsin D released from lysosomes mediates apoptosis

   Författare :Katarina Kågedal; Marja Jäättelä; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Last year (2002), the Nobel Prize in Physiology or Medicine was awarded to three scientists who have conducted pioneer research on programmed cell death. In the human body, more than a thousand billion cells are created every day, and an equal number die, thus programmed cell death, or apoptosis, is an important mechanism for maintaining tissue homeostasis and protecting against disease. LÄS MER