Sökning: "Linkage"

Visar resultat 21 - 25 av 615 avhandlingar innehållade ordet Linkage.

  1. 21. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches

    Författare :Cecilia Lindgren; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single nucleotide polymorphism SNP ; transmission-disequilibrium test TDT ; genetic variation; single strand conformational polymorphism SSCP ; gene expression; insulin; glucose; genome-wide scan; linkage; genetic association; Type 2 diabetes; early onset diabetes EOD ; sekretion; diabetologi; Endokrinologi; diabetology; Endocrinology; secreting systems; signal-to-noise ratio SNR ;

    Sammanfattning : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. LÄS MER

  3. 22. Genetic Studies of Rheumatoid Arthritis using Animal Models

    Författare :Niklas Nordquist; William Dietrich; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Complex disease; autoimmune; rheumatoid arthritis; genetic; mapping; QTL; locus; linkage; animal model; rat; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Predisposition to autoimmune diseases such as, rheumatoid arthritis, diabetes, and multiple sclerosis, is caused by the effect of multiple genes and a strong influence from the environment. In this study, I have investigated genetic factors that confer susceptibility to rheumatoid arthritis in a rat model. LÄS MER

  4. 23. The genetic complexity of celiac disease. Gene variants linked and associated to an inflammatory autoimmune disorder

    Författare :Åsa Torinsson Naluai; Göteborgs universitet; []
    Nyckelord :Celiac disease; genome-wide scan; linkage; association; complex disease; autoimmune; CTLA4; 5q31-33; polymorphism;

    Sammanfattning : .... LÄS MER

  5. 24. Linkage maps in studies of genetic variation - examples from Beta vulgaris

    Författare :Thomas Kraft; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytogenetics; Genetics; Beta vulgaris; Linkage maps; genetic variation; Genetik; cytogenetik;

    Sammanfattning : Today, most studies of genetic variation utilise molecular markers, making it possible to detect variation at the DNA level. This has greatly facilitated studies of genetic variation in population and evolutionary genetics, systematics and transmission genetics. LÄS MER

  7. 25. Two contributions to genetic linkage analysis

    Författare :Staffan Nilsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER