Sökning: "CTLA4"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet CTLA4.

  1. 1. The genetic complexity of celiac disease. Gene variants linked and associated to an inflammatory autoimmune disorder

    Författare :Åsa Torinsson Naluai; Göteborgs universitet.; Gothenburg University.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Celiac disease; genome-wide scan; linkage; association; complex disease; autoimmune; CTLA4; 5q31-33; polymorphism;

    Sammanfattning : .... LÄS MER

  2. 2. Biologics in Staphylococcus aureus arthritis

    Författare :Abukar Ali; Göteborgs universitet.; Gothenburg University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; CTLA4-Ig; IL-1 Ra; anti-TNF therapy; mouse; septic arthritis;

    Sammanfattning : The emergence of new type of drugs known as biologics has led to rapid disease improvements in many autoimmune arthritic patients. Nevertheless, most of these biologics are immunomodulators that may consequently increase the susceptibility of patients towards infections, such as septic arthritis. LÄS MER

  3. 3. Heritable modulators of the multiple sclerosis phenotype

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Neuroscience, Occupational Therapy and Elderly Care Research (NEUROTEC)

    Författare :Thomas Masterman; Karolinska Institutet.; Karolinska Institutet.; [2002]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Studies of families in which more than one case of multiple sclerosis (MS) occurs have demonstrated that shared genetic and/or environmental factors appear to modify clinical features of the disease, including rate of progression and disease course. We undertook in the present project to determine to what extent selected genetic factors constitute heritable determinants of the MS phenotype. LÄS MER

  4. 4. Clinical and genetical aspects of Celiac Disease

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Audur Gudjonsdottir; Göteborgs universitet.; Gothenburg University.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; celiac disease; sib-pair; screening; genome-wide scan; linkage analysis; heritability; genotypes; DQ2-negative; phenotypes; autoimmune disease;

    Sammanfattning : Celiac disease (CD), or gluten-sensitive enteropathy, is one of the most common chronic diseases in childhood but is diagnosed in all ages. CD is a genetically driven immunological intolerance to dietary gluten. Th e treatment is a gluten-free diet. LÄS MER

  5. 5. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Detta är en avhandling från Stockholm : Wenner-Grens institut för experimentell biologi

    Författare :Valentina D Mangano; Stockholms universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Sammanfattning : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. LÄS MER