Sökning: "Isothermal Amplification Methods"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Isothermal Amplification Methods.

  1. 1. Visual and magnetic detection of antimicrobial resistance genes using nanoparticles and isothermal amplification

    Författare :Darío Sánchez Martín; Teresa Zardán Gómez de la Torre; Maria Strömme; Mahiar Hamedi; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; DNA amplification; isothermal amplification; visual detection; nanoparticles; VAM-NDA; rolling circle amplification; phi29 DNA polymerase; padlock probes.; Teknisk fysik med inriktning mot nanoteknologi och funktionella material; Engineering Science with specialization in Nanotechnology and Functional Materials;

    Sammanfattning : Antibiotic resistance is becoming an increasing concern, necessitating new ways to diagnose and treat it rapidly and accurately. One proposed solution is the use of nucleic acid amplification tests, capable of detecting resistance in just a few hours, as opposed to the several days that traditional testing methods may require. LÄS MER

  3. 2. Padlock Probe-Based Nucleic Acid Amplification Tests : Point-of-care Diagnostics of Infectious Diseases

    Författare :Sibel Ciftci; Mats Nilsson; Jonas Klingström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nucleic Acid Amplification; Isothermal Amplification Methods; Padlock Probes; Rolling Circle Amplification; Molecular Diagnostics; Infectious Disease Diagnostics; Virus; Point-of-Care; Biochemistry; biokemi;

    Sammanfattning : Recent advancements in molecular biology and biotechnology have pushed the field of molecular diagnostics much further to benefit the society towards smart access for rapid and simplified health care. In this context, point-of-care (PoC) technologies that bring the inventions in diagnostics closer to bedside settings draw attention. LÄS MER

  4. 3. Advancing isothermal nucleic acid amplification tests : Towards democratization of diagnostics

    Författare :Felix Neumann; Mats Nilsson; Paul Yager; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molecular diagnostics; infectious diseases; point-of-care; digital quantification; fluorescence detection; rolling circle amplification; padlock probes; microfluidic enrichment; Biochemistry; biokemi;

    Sammanfattning : Modern healthcare is the result of scientific advancement across disciplines and has enabled us to understand the rationale behind many diseases and how to treat or cure them; but still a myriad of unanswered questions remains. Especially infectious diseases play an important role in healthcare as they pose a constant threat for global health and well-being. LÄS MER

  5. 4. Sample-to-answer paper-based nucleic acid amplification tests

    Författare :Georgios Chondrogiannis; Mahiar Hamedi; Jeff Mold; Keith Pardee; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Nucleic Acid Amplification Tests (NAATs) with PCR technology to amplify DNA, are the golden standard for infectious disease diagnostics, but they require benchtop instruments and trained users to be performed. For this reason, we all had to send PCR test to centralized laboratories during the Covid-19 pandemic. LÄS MER

  7. 5. Molecular methods in malaria control in the era of pre-elimination

    Författare :Ulrika Morris; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Increased funding combined with effective malaria control methods for prevention, diagnosis, and treatment, has resulted in a 30% reduction of the global malaria burden over the last decade. As malaria prevalence declines in areas of successful malaria control, the proportion of subpatent infections that fall below the detection level of malaria rapid diagnostic tests (RDTs) and microscopy increases. LÄS MER