Sökning: "Gisela Helenius"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Gisela Helenius.

  1. 1. Tissue engineering in blood vessels

    Författare :Gisela Helenius; Göteborgs universitet; []
    Nyckelord :tissue engineering; vascular graft; endothelial cells; smooth muscle cells; thrombogenicity; mechanical properties; scaffold; bacterial cellulose;

    Sammanfattning : Severely occluded coronary- and peripheral arteries, caused by atherosclerotic plaques, are treated with bypass surgery. Autologous veins are the most commonly used replacement graft. Among the patients that need a vascular bypass, 5-10% lack appropriate replacement veins due to previous surgery of bad quality of the vessels. LÄS MER

  3. 2. Cervical screening with primary HPV : from research to clinical effectiveness

    Författare :Lovisa Bergengren; Gisela Helenius; Mats Karlsson; Matts Olovsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cervical cancer; screening; human papillomavirus HPV ; HPV prevalence; HPV genotypes; precancerous lesion; HSIL; self-sampling; postmenopausal women; health economy;

    Sammanfattning : Organized cervical screening has greatly reduced the incidence of cervical cancer where implemented. Human papilloma virus (HPV) is the cause of cervical cancer, and in later years, convincing evidence has led to cervical screening with HPV as the primary method being implemented around the world. LÄS MER

  4. 3. Identification of miRNA expression profiles for diagnosis and prognosis of prostate cancer

    Författare :Jessica Carlsson; Karin Klinga Levan; Björn Olsson; Gisela Helenius; Pernilla Wikström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; microRNAs; prostate zones; normalization; endogenous controls; Medicin; Medicine;

    Sammanfattning : Cancer of the prostate (CaP) is the most common malignancy diagnosed in men in the Western society. During the last years, prostate specific antigen (PSA) has been used as a biomarker for CaP, although a high PSA value is not specific for CaP. Thus, there is an urgent need for new and improved diagnostic markers for CaP. LÄS MER

  5. 4. Infection induced chronic inflammation and it's association with prostate cancer initiation and progression

    Författare :Sabina Davidsson; Ove Andrén; Bo Söderquist; Jennifer Rider; Gisela Helenius; Jan-Erik Damber; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chronic inflammation; CD4 helper T cells; CD8 cytotoxic T cells; regulatory T cells; Propionibacterium acnes; Medicine; Medicin;

    Sammanfattning : An association between cancer development and inflammation has long been suggested. Approximately 20% of all human cancers in adults are assumed to result from chronic inflammation. The aim of this thesis was to investigate if infection-induced chronic inflammation plays a role in prostate carcinogenesis. LÄS MER

  7. 5. Clinical studies of RNA as a prognostic and diagnostic marker for disease

    Författare :Helena Isaksson; Torbjörn Nilsson; Bengt Sorbe; Gisela Helenius; Ola Hammarsten; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gene expression; ovarian cancer; hypercalprotectinaemia; hyperzincaemia; ischemia; biomarker;

    Sammanfattning : Technologies for RNA detection are evolving rapidly and gives an op-portunity for discovery of new markers for early detection of complex diseases. Today in clinical work we rely on signs and symptoms in com-bination with the measurement of protein levels for diagnosis. LÄS MER