Sökning: "Gamma irradiation"

Visar resultat 16 - 20 av 37 avhandlingar innehållade orden Gamma irradiation.

  1. 16. Factors modifying cellular response to ionizing radiation

    Författare :Lei Cheng; Andrzej Wojcik; Siamak Haghdoost; Lovisa Lundholm; Penelope A. Jeggo; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiation biology; DNA damage; gene expression; alpha particles; X-rays; mixed beams; gamma rays; hypothermia; dose rate.; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Many physical factors influence the biological effect of exposure to ionizing radiation, including radiation quality, dose rate and temperature. This thesis focuses on how these factors influence the outcome of exposure and the mechanisms behind the cellular response. LÄS MER

  3. 17. The GLAST Satellite Calorimeter

    Författare :Georg Johansson; Avdelningen för Biomedicinsk teknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; GLAST; CsI Tl crystals; electromagnetic calorimeter; hodoscopic assembly; satellite-born detector; Dark Matter; cosmic gamma radiation;

    Sammanfattning : The Gamma Ray Large Area Space Telescope (GLAST) is a multi-national satellite mission with aim to study the high-energy gamma ray sky. The main instrument is the Large Area Telescope (LAT) that consists of 16 towers, each housing a silicon strip precision tracker and a CsI(Tl) calorimeter. LÄS MER

  4. 18. Short and long-term effects of exposure to low dose and low dose rate of gamma radiation : using in vitro and in vivo models

    Författare :Traimate Sangsuwan; Siamak Haghdoost; Eva Forssell-Aronsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Low dose; Low dose rate; High dose rate; Ionizing radiation; Adaptive response; Senescence; Premature senescence; Oxidative stress; Drosophila embryo; Mutation; DNA repair; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Assessment of human health risks from exposure to ionizing radiation (IR) is mainly based on the extrapolation of results from epidemiological studies on populations exposed to relatively high doses and often at high dose rates (HDR). Risk estimates after exposure to low doses and in particular at low dose rates (LDR) remain controversial due to a lack of epidemiological evidence. LÄS MER

  5. 19. Induction and repair of DNA double-strand breaks in human cells exposed to different radiation qualities

    Författare :Irina Radulescu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DSB; chromatin structure; high-LET; heat-labile sites; PFGE; DNA-PKcs; XRCC1; PARP-1; pATM; gamma-H2AX; 53BP1;

    Sammanfattning : Radiation therapy is used in attempting to kill tumor cells by inducing DNA double- strand breaks (DSB), the most critical DNA lesions. Recent and planned radiation therapy strategies use high-linear energy transfer (LET) radiation to effectively treat malignant tumors. LÄS MER

  7. 20. New approaches to preparation and storage of platelets

    Författare :Stella Larsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During the last century, transfusion of blood components has become a prerequisite for treatment in many clinical settings. The availability of plastic bags and methods for centrifugation and separation of blood cells, has enabled processing of whole blood into blood cell components, and made it possible to optimize transfusion therapy, as well as storage conditions. LÄS MER