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Visar resultat 1 - 5 av 24 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Chronic obstructive pulmonary disease (COPD) : prevalence, incidence, decline in lung function and risk factors

    Författare :Anne Lindberg; Bo Lundbäck; Rune Lundgren; Lars-Gunnar Larsson; Sven Larsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Chronic Obstructive Pulmonary Disease; Prevalence; Incidence; Decline in Lung Function; Risk Factors; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; lungmedicin; Lung Medicine;

    Sammanfattning : The Obstructive Lung Disease in Northern Sweden (OLIN) Studies started in 1985 as an epidemiological project with the aim to detect preventable risk factors for obstructive lung diseases and allergy. In recent years there has been a focus also on obstructive sleep apnoea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD) besides asthma and allergy. LÄS MER

  2. 2. Inflammation in asthma: relation to symptomatology, exacerbations and lung function

    Författare :Ida Mogensen; Andrei Malinovschi; Christer Jansson; Mona Bafadhel; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; eosinophil; eosinophil cationic protein; eosinophil derived neurotoxin; periostin; neutrophil; fixed airflow obstruction; lung function; asthma attack; asthma symptom;

    Sammanfattning : Asthma is an inflammatory disease in the airways. It is characterized by respiratory symptoms such as wheezing, variable airflow obstruction and impaired lung function development. A better understanding of the underlying inflammation is crucial in order to treat and prevent asthma symptoms and lung function deterioration. LÄS MER

  3. 3. Lung function in relation to exercise capacity in health and disease

    Författare :Amir Farkhooy; Andrei Malinovschi; Christer Janson; Hans Hedenström; Harrpa Arnardottir; Ann Ekberg Jansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exercise capacity; Exercise test; Lung function; Spirometri; Diffusion capacity; COPD; Pulmonary hypertension; Clinical Physiology; Klinisk fysiologi;

    Sammanfattning : Background: Exercise capacity (EC) is widely recognized as a strong and independent predictor of mortality and disease progression in various diseases, including cardiovascular and pulmonary diseases. Furthermore, it is generally accepted that exercise capacity in healthy individuals and in patients suffering from cardiovascular diseases is mainly limited by the maximum cardiac output. LÄS MER

  4. 4. Lung function in alpha1-antitrypsin deficiency

    Författare :Eeva Piitulainen; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alpha1-antitrypsin deficiency. Lung function. Register. Risk factors. Lung disease. Natural course.; Respiratory system; Andningsorganen;

    Sammanfattning : Hereditary alpha1-antitrypsin (AAT) deficiency predisposes to liver disease and emphysema. The aims of the studies upon which thesis is based were to investigate the natural course of lung function and risk factors for lung disease in AAT-deficient adolescents (PiZZ and PiSZ) and adults (PiZZ), and to study clinical manifestations in AAT-deficient adults. LÄS MER

  5. 5. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation

    Författare :P. Abigail Alvarado-Vazquez; Jenny Hallgren; Arne Egesten; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; mast cell progenitors; pulmonary function test; allergic airway inflammation; experimental asthma model; Immunologi; Immunology;

    Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER