Sökning: "DNA-sequencing"

Visar resultat 21 - 25 av 144 avhandlingar innehållade ordet DNA-sequencing.

1. 21. Fungal molecular ecology in boreal forests and challenges associated with unidentified environmental DNA sequences

   Författare :Kerri Kluting; Anna Rosling; Martin Ryberg; Sara Branco; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; amplicon sequence variant ASV ; Archaeorhizomycetes; environmental DNA sequencing; high-throughput sequencing; integrative taxonomy; pine forest; podzol soil profile; Pucciniomycotina; Tomicus piniperda; voucherless specimens; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : Many fungi are characteristically difficult to observe and collect, making the process of documenting the world’s fungal diversity challenging. The vast majority of fungal species are undescribed. LÄS MER

3. 22. Engineering cytosolic acetyl-CoA metabolism in Saccharomyces cerevisiae

   Författare :Yiming Zhang; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; reverse engineering; flavodoxin; genomic DNA sequencing; ferredoxin; histone deacetylase; adaptive evolution; ferredoxin flavodoxin NADP reductase; pyruvate decarboxylase; citrate synthase; hexose transporter; yeast; mitochondria; aerobic growth; metabolic engineering.; acetyl-CoA; central carbon metabolism;

   Sammanfattning : A Saccharomyces cerevisiae strain carrying deletions in all three pyruvate decarboxylase genes (also called Pdc negative yeast) represents a non-ethanol producing platform strain for biochemical production. However, it cannot grow on glucose as the sole carbon source due to the lack of cytosolic acetyl-CoA for lipid biosynthesis. LÄS MER

4. 23. Clinical and genetic studies of patients and families with ataxia

   Författare :Sorina Gorcenco; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hereditary ataxia; Next generation DNA sequencing; Diagnostic yield; Quality of life;

   Sammanfattning : .... LÄS MER

5. 24. Variational methods for phylogeny and single-cell genomics

   Författare :Hazal Koptagel; Jens Lagergren; Alexandre Bouchard-Côté; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Variational inference; single-cell DNA sequencing; cell lineage tree; Bayesian phylogenetic tree inference; Variationsinferens; encellig DNA-sekvensering; cellhärkomstträd; Bayesiansk fylogenetisk trädinferens; Varyasyonel çıkarım; tek hücre DNA dizilimi; hücre soy ağacı; Bayesçi filogenetik ağaç çıkarımı; Datalogi; Computer Science;

   Sammanfattning : The investigation of the evolutionary history of organisms, both at the cellular level and at the species level, is a relevant research topic in computational biology. These investigations lead to a deeper understanding of developmental history, cancer progression, the genetic similarity of species, and more. LÄS MER

7. 25. Comparative sequencing of candidate genes in complex disease

   Författare :Shane McCarthy; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :DNA; Sequencing; Complex Disease; Candidate Gene;

   Sammanfattning : Complex multi-factorial diseases such as cardiovascular, metabolic, neurological and respiratory disorders affect a great number of people across the world. In the post-Human Genome Sequencing era, genome wide association studies are increasingly viable alternatives to linkage approaches in locating disease genes. LÄS MER