Sökning: "Causal inference"

Visar resultat 6 - 10 av 59 avhandlingar innehållade orden Causal inference.

1. 6. Elucidating causal relationships between energy homeostasis and cardiometabolic outcomes

   Författare :Pascal Mutie; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adiposity; causal inference; Cardiometabolic disease; Mendelian randomization;

   Sammanfattning : Energy metabolism dyshomeostasis is associated with multiple health problems. For example, abundant epidemiological data show that obesity and overweight increase the risk of cardiometabolic diseases and early mortality. LÄS MER

3. 7. Searching for causal effects of road traffic safety interventions : applications of the interrupted time series design

   Författare :Carl Bonander; Ragnar Andersson; Finn Nilson; Claes Tingvall; Karlstads universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Causal inference; Repeated measures; Methodology; Econometrics; Injury Epidemiology; Vulnerable Road Users; Time series analysis; Risk- och Miljöstudier; Risk and Environmental Studies;

   Sammanfattning : Traffic-related injuries represent a global public health problem, and contribute largely to mortality and years lived with disability worldwide. Over the course of the last decades, improvements to road traffic safety and injury surveillance systems have resulted in a shift in focus from the prevention of motor vehicle accidents to the control of injury events involving vulnerable road users (VRUs), such as cyclists and moped riders. LÄS MER

4. 8. Robust inference of gene regulatory networks : System properties, variable selection, subnetworks, and design of experiments

   Författare :Torbjörn E. M. Nordling; Elling W Jacobsen; Rolf Findeisen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; network inference; reverse engineering; variable selection; model selection; feature selection; subset selection; system identification; system theory; network theory; subnetworks; design of experiments; perturbation experiments; gene regulatory networks; biological networks;

   Sammanfattning : In this thesis, inference of biological networks from in vivo data generated by perturbation experiments is considered, i.e. deduction of causal interactions that exist among the observed variables. Knowledge of such regulatory influences is essential in biology. LÄS MER

5. 9. Causal Inference: Applications in Education, Violence, and the Scientific Process

   Författare :Felix Schafmeister; Handelshögskolan i Stockholm; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

   Sammanfattning : This thesis consists of five self-contained chapters. In chapter 1, I analyze how replications affect how underlying studies are cited. My results provide no evidence that citations changed in response to either successful or failed replications, with potentially worrying implications for the self-corrective ability of the scientific process. LÄS MER

7. 10. Enhancing prediction and causal inference in metabolic dyshomeostasis

   Författare :Naeimeh Atabaki Pasdar; Genetisk och molekylär epidemiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : This thesis is focused on two globally prevalent diseases: i) non-alcoholic fatty liver disease (NAFLD) and ii) type 2 diabetes (T2D), with an overall aim of improving prediction and causal inference in the context of these conditions. Our projects were mainly conducted using IMI DIRECT and UK Biobank datasets including multi-omics data, extensive environmental exposures, and biological intermediates. LÄS MER