Sökning: "gene regulatory networks"

Visar resultat 1 - 5 av 89 avhandlingar innehållade orden gene regulatory networks.

1. 1. Gene Regulatory Networks: Dynamics and Stability

   Författare :Carl Troein; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; systems; control; Datalogi; numerisk analys; system; kontroll; Computer science; numerical analysis; Fysik; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Physics; medical informatics; transcriptional regulation; gene regulatory networks; Bioinformatics; signaling pathway profiling; stem cell regulation; metabolic pathway; fitness; nested canalyzing rules; Kauffman networks; random Boolean networks; Fysicumarkivet:2007:Troein;

   Sammanfattning : Life as we know it is based on cells that use proteins and RNA to carry out metabolism, self-replication, and other essential tasks. The genes that code for these molecules are encoded in DNA, and through the processes of transcription and translation the cell expresses its genes. LÄS MER

3. 2. Robust inference of gene regulatory networks : System properties, variable selection, subnetworks, and design of experiments

   Författare :Torbjörn E. M. Nordling; Elling W Jacobsen; Rolf Findeisen; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; network inference; reverse engineering; variable selection; model selection; feature selection; subset selection; system identification; system theory; network theory; subnetworks; design of experiments; perturbation experiments; gene regulatory networks; biological networks;

   Sammanfattning : In this thesis, inference of biological networks from in vivo data generated by perturbation experiments is considered, i.e. deduction of causal interactions that exist among the observed variables. Knowledge of such regulatory influences is essential in biology. LÄS MER

4. 3. On gene regulatory networks and data fitting

   Författare :Karl Fogelmark; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
   Nyckelord :Circadian rhythms; gene regulation; transcription networks; correlated data; Circadian rhythms; gene regulation; transcription networks; correlated data; Fysicumarkivet A:2016:Fogelmark;

   Sammanfattning : Living organisms can be viewed as complex biological machines. In order to function, they must regulate their internal mechanism to do the right thing, at the right time, and in the right amount. Part of this regulation is encoded in gene regulatory networks. LÄS MER

5. 4. Exploring the Boundaries of Gene Regulatory Network Inference

   Författare :Andreas Tjärnberg; Erik Sonnhammer; Richard Bonneau; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; GRN; gene regulatory network; network inference; signal to noise ratio; model selection; variable selection; data properties; reverse engineering; ordinary differential equations; gene networks; linear regression; lasso; Biochemistry towards Bioinformatics; biokemi med inriktning mot bioinformatik;

   Sammanfattning : To understand how the components of a complex system like the biological cell interact and regulate each other, we need to collect data for how the components respond to system perturbations. Such data can then be used to solve the inverse problem of inferring a network that describes how the pieces influence each other. LÄS MER

7. 5. Dynamics in Random Boolean Networks

   Författare :Björn Samuelsson; Funktionell zoologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gravitation; relativity; quantum mechanics; biomathematics biometrics; Bioinformatik; medicinsk informatik; biomatematik; Mathematical logic; set theory; combinatories; Matematisk logik; Mathematical and general theoretical physics; kombinatorik; mängdlära; classical mechanics; Bioinformatics; tissue simulations; transcription networks; random graphs; random maps; nested canalyzing; canalyzing; genetic regulation; Kauffman networks; random Boolean networks; statistical physics; thermodynamics; medical informatics; Matematisk och allmän teoretisk fysik; klassisk mekanik; kvantmekanik; relativitet; termodynamik; statistisk fysik;

   Sammanfattning : There are many examples of complex networks in science. It can be genetic regulation in living cells, computers on the Internet, or social and economic networks. In this context, Boolean networks provide simplistic models that are relatively easy to handle using computer simulations and mathematical methods. LÄS MER