Sökning: "Catherine L. Merry"

Hittade 2 avhandlingar innehållade orden Catherine L. Merry.

1. 1. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

   Författare :Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

   Sammanfattning : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. LÄS MER

3. 2. In Vitro Studies of the Substrate Specificities of Heparan Sulfate 2-O- and 6-O-sulfotransferases

   Författare :Emanuel Smeds; Marion Kusche-Gullberg; Ulf Lindahl; Catherine L. R. Merry; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparan sulfate; heparin; sulfotransferase; 2-O-sulfotransferase; 6-O-sulfotransferase; polysaccharide biosynthesis; glycosaminoglycan; O-sulfotransferase; proteoglycan; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : Heparan sulfate (HS), a linear negatively charged polysaccharide located at the cell surface and in the extracellular matrix, interacts with, and thereby regulates the functions of numerous proteins. HS-protein interactions depend on the fine structure of HS, especially its sulfation pattern. LÄS MER