Sökning: "Bertil Kågedal"

Hittade 3 avhandlingar innehållade orden Bertil Kågedal.

  1. 1. Microdialysis as a Tool in Studies of L-Dopa and Metabolites in Malignant Melanoma and Parkinson’s Disease

    Författare :Nil Dizdar (Dizdar Segrell); Bertil Kågedal; Jan-Edvin Olsson; Christer Hansson; Linköpings universitet; []
    Nyckelord :Microdialysis; L-Dopa; Malignant Melanoma; Parkinson s Disease; in vivo; MEDICINE; MEDICIN;

    Sammanfattning : A model with human melanoma xenografts transplanted to athymic mice has been adopted for in vivo studies of 5-S-cysteinyldopa (an intermediate pigment metabolite), glutathione, and cysteine. L-Dopa is an intermediate metabolite in pigment formation and is also important in the treatment of Parkinson's disease, and therefore 1 have also studied the pharmacokinetics of this compound. LÄS MER

  3. 2. Homocysteine in cardiovascular disease with special reference to longitudinal changes

    Författare :Johan Hultdin; Torbjörn Nilsson; Bertil Kågedal; Umeå universitet; []
    Nyckelord :Medical sciences; homocysteine; methylenetetrahydrofolate reductase MTHFR ; first-ever stroke; first-ever myocardial infarction; longitudinal; prospective; risk factor; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Abnormalities in homocysteine metabolism have been suggested as risk factors for stroke and myocardial infarction. In retrospective studies, elevated levels of total plasma homocysteine (tHcy) and/or methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism have indicated an increase in risk. LÄS MER

  4. 3. Pheomelanin markers in melanoma with reference to their excretion into urine

    Författare :Dzeneta Nezirevic Dernroth; Bertil Kågedal; Christer Hansson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pheomelanin; melanoma; benzothiazole; aminohydroxyphenylalanine; diffuse melanosis; HILIC; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Skin pigmentation is an important issue in most cultures. Until recently we have not understood the most important elements of pigmentation regarding detailed chemical structure. LÄS MER