Sökning: "A receptors"
Visar resultat 1 - 5 av 2292 avhandlingar innehållade orden A receptors.
1. Signaling via Orexin Receptors : A Pharmacological Study
Sammanfattning : The orexin receptors are a pair of newly discovered G-protein coupled receptors which are activated by the neuropeptides orexins and play a role in sleep/vigilance, apetite/metabolism and neuroendocrine regulation. On a cellular level receptor activation results in, to name but a few effects, elevation of intracellular calcium and depolarisation. LÄS MER
2. Hyaluronan receptors of liver endothelial cells, their purification and characterisation
Sammanfattning : Hyaluronan (HA) is a polysaccharide common throughout the connective tissues. and is found at low concentrations in the blood. The major site of its clearance is via an endocytic receptor on liver endothelial cells (LEC). This process is vital, as excessive serum levels of HA lead to clotting disorders and overly viscous blood. LÄS MER
3. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection
Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER
4. Hematopoiesis, Kazal Inhibitors and Crustins in a Crustacean
Sammanfattning : Hemocytes are important as storage and producers of proteins of the innate immune defence, as well as actors of the cellular immune response. Therefore the hematopoietic process is critical for survival of most invertebrates. LÄS MER
5. Magnetic bead-based isolation of biological therapeutic modalities
Sammanfattning : Biopharmaceutical modalities, such as monoclonal antibodies or the less established cell therapies, are nowadays very important for the treatment of severe or incurable diseases. The manufacturing of such modalities is complex and costly, including the downstream processing, which is highly essential to ensure the safety and quality of the product. LÄS MER