Sökning: "karolinska 2016"
Visar resultat 16 - 20 av 439 avhandlingar innehållade orden karolinska 2016.
16. Stem cell in-vitro strategies for the induction of sensory neurons for inner ear cell therapy
Sammanfattning : The cochlea, a part of the auditory system, is a complex structure consisting of several different types of cells including hair cells and spiral ganglion neurons. In mammals, the regenerative potential of hair cells and spiral ganglion neurons is lost soon after the birth and damage to any of these cells causes sensorineural hearing loss. LÄS MER
17. Novel genetic associations with common variable immunodeficiency
Sammanfattning : Common variable immunodeficiency (CVID) is the most frequently encountered primary immunodeficiency disorder in clinical practice and is a cause of significant morbidity and mortality for patients. The main clinical features are hypogammaglobulinemia, recurrent infections and autoimmune disorders. LÄS MER
18. Conditions associated with increased growth hormone and prolactin sensitivity
Sammanfattning : Growth Hormone (GH) and Prolactin (PRL) are critical regulators of body growth and metabolism. Secretion and actions of GH and PRL are regulated at several levels and by different factors. The biological actions of these hormones are initiated by their binding to the respective membrane bound receptors of GH and PRL (GHR and PRLR). LÄS MER
19. Rapid diagnosis of sepsis pathogens
Sammanfattning : Sepsis is a growing global healthcare concern and is related to high morbidity and mortality. Studies have repeatedly demonstrated that the rapid administration of appropriate antimicrobial treatment is crucial for patient survival. LÄS MER
20. Actin and myosin in transcription and chromatin regulation
Sammanfattning : In mammalian cells, actin and myosin have emerged as regulators of nuclear structure and function, involved in chromatin remodeling and histone modifications, and in different phases of gene transcription. Actin and myosin have also been shown to be incorporated into nascent ribonucleoprotein complexes. LÄS MER