Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Brain galanin sytems and their role in depression-like behaviour

   Författare :Eugenia Kuteeva; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :5-HT1A receptor; depression-like behaviour; forced swim test; galanin; galanin-overexpressing; galanin receptor; noradrenaline; serotonin; transgenic mouse;

   Sammanfattning : The aim of the present thesis was to investigate the role of the neuropeptide galanin and galanin receptor subtypes in behavioural functions with a particular focus on depression-like behaviour. In agreement with its wide distribution in the central nervous system, galanin has been implicated in various functions, including regulation of reproduction, endocrine functions, antinociception, attention, learning and memory as well as regulation of mood. LÄS MER

3. 2. Alterations in circadian entrainment : translational value in major depression

   Författare :Frederik Elberling; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Adverse conditions of different origin occurring during development can have a negative impact on the nervous system and increase risk for the onset of mental disorders. In mice prenatal exposure to excess glucocorticoids (GC) leads to late onset depression-like behaviour in males which is preceded by alterations in circadian entrainment. LÄS MER