Sökning: "Sten Orrenius"

Hittade 1 avhandling innehållade orden Sten Orrenius.

1. 1. The Lysosomal-Mitochondrial Axis Theory of Apoptosis

   Författare :Ming Zhao; Sten Orrenius; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : In many cases, apoptosis may be initiated by a minor lysosomal destabilization, which some time later is followed by a secondary, more pronounced, lysosomal rupture. After exposure to low concentrations of sphingosine, a lysosomotropic detergent, Jurkat and J774 cells underwenr apoptotic cell death, while cells exposed to higher concentrations of this agent showed necrosis. LÄS MER