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1. 1. Regional differences in the response of neural stem cells and their microenvironment to ionizing radiation

   Författare :Nina Hellström; Göteborgs universitet; []
   Nyckelord :ionizing radiation; neurogenesis; neural stem cells; inflammation; microglia; stem cell niche; trophic support;

   Sammanfattning : Radiation therapy is one of the most effective tools for treating malignant tumors; however, cranial irradiation often results in intellectual impairment and cognitive deficits, such as impaired learning and memory. Ionizing radiation generates DNA damage, causing proliferative cells to undergo apoptosis. LÄS MER