Sökning: "Pair 19 genetics"

Hittade 4 avhandlingar innehållade orden Pair 19 genetics.

  1. 1. On Speciation in Birds – Genomic Signatures across Space and Time

    Detta är en avhandling från Department of Biology, Lund University

    Författare :Martin Stervander; Lund University.; Lunds universitet.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; colonization; islands; isolation; introgressive hybridization; sympatry; natural selection; bill morphology; coalescence-based analyses; DNA sequencing; birds; divergence; Speciation;

    Sammanfattning : The process of speciation is a cornerstone in evolutionary biology. In Darwin’s On the Origin of Species, he described how he imagined that a new species would evolve to fill an empty niche. This focus on ecology shifted with Mayr towards the importance of isolation, and for many decades the geographic modes of speciation were debated. LÄS MER

  2. 2. Exploring next-generation sequencing in chronic lymphocytic leukemia

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Viktor Ljungström; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CLL; next-generation sequencing; clonal evolution; stereotypy; RPS15; NFKBIE; Medical Genetics; Medicinsk genetik;

    Sammanfattning : Next-generation sequencing (NGS) techniques have led to major breakthroughs in the characterization of the chronic lymphocytic leukemia (CLL) genome with discovery of recurrent mutations of potential prognostic and/or predictive relevance. However, before NGS can be introduced into clinical practice, the precision of the techniques needs to be studied in better detail. LÄS MER

  3. 3. Inflammatory bowel disease in twins : studies of genetics and environmental factors

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Jonas Halfvarson; Linköpings universitet.; Linköpings universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : The aetiology of inflammatory bowel disease (IBD) is unknown but considered to be caused by interplay of genetic and environmental factors.The aims of this thesis were to study the influence of genetics and environmental factors in aetiology, disease phenotype and levels of Anti-Saccharomyces cerevisiae antibodies (ASCA), as well as to assess whether CARD15/NOD2 polymorphisms explain the influence of genetics in these aspects. LÄS MER

  4. 4. From gene mutation to gene expression : studies on multiple endocrine neoplasia type 1 and vascular endothelial growth factors

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Molecular Medicine and Surgery

    Författare :Emma Tham; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple endocrine neoplasia type 1; mutation detection; Vascular Endothelial Growth Factors; recombinant protein; dilated cardiomyopathy; multiple sclerosis;

    Sammanfattning : Multiple Endocrine Neoplasia type 1, MEN1, is an inherited cancer syndrome whose gene was localised to chromosome 11q13 in 1988. A number of !candidate genes were characterised before the MEN1 gene was cloned in 1997. DNA sequencing of MEN1 to search for mutations in patients is used as a complement to clinical diagnosis. LÄS MER