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1. 1. Exploring novel therapeutic strategies in neuroblastoma

   Författare :Joanna Szydzik; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Neuroblastoma; Anaplastic Lymphoma Kinase; Targeted therapy; ATR inhibition;

   Sammanfattning : Neuroblastoma (NB) is the most frequently diagnosed extracranial tumour in children, which arises from transient embryonal tissue of the neural crest that fails to complete terminal differentiation into neurons. Even after completion of successful therapy, high risk neuroblastoma patients typically suffer from post-treatment induced toxicity which impacts on their ability to lead a normal life. LÄS MER