Sökning: "virological failure"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden virological failure.

  1. 1. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects

    Författare :Erik Sörstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; transient viremia; viral blip; nucleoside transcriptase inhibitor resistance; dolutegravir; baseline viral load; HIV RNA; virological failure;

    Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER

  3. 2. Enhanced antiretroviral treatment support in relation to quality of life and virological failure in low income setting : a cluster randomized controlled trial in Quang Ninh, Vietnam

    Författare :Van Tam Vu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Antiretroviral therapy (ART) has become more widely available in Vietnam since 2005. However, up to now, very little is known about characteristics of people living with HIV (PLHIV) at ART initiation including factors influencing ART adherence. LÄS MER

  4. 3. Kinetics of HIV-1 drug resistance mutations in vivo

    Författare :Veronica Svedhem Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV-1; anti-retroviral therapy; drug resistance; therapy failure; rebound; persistence; wildtype virus; SPCR; minor population;

    Sammanfattning : Antiretroviral therapy (ARV) exert a selective pressure on HIV-1 and may select viral drug resistant strains which have competitive advantage in the presence of the drug. Knowledge about the appearance and disappearance of these mutations is important when choosing ARV. LÄS MER

  5. 4. Influencing HIV treatment success in India : do mobile phones really work?

    Författare :Anita Shet; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV;

    Sammanfattning : Background: Sustaining treatment adherence and long-term virological suppression is a global health challenge in HIV management. Mobile phone-based interventions are increasingly harnessed to enhance medication adherence in HIV infection, although supporting evidence for implementation is limited by lack of robust efficacy trials in settings such as India. LÄS MER

  7. 5. The HIV-1 epidemic in Ethiopia – transmission patterns, antiretroviral drug resistance and treatment outcomes

    Författare :Dawit Assefa; Malmö Klinisk virologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV drug resistance HIVDR ; Phylodynamics; Phylogenetic; Molecular epidemology; transmitted HIVDR; acquired HIVDR; pre-treatment HIVDR; Integrase strand transfer inhibitors INSTI ; Ethiopia; antiretroviral therapy;

    Sammanfattning : A comprehensive understanding of local HIV epidemiology is essential for monitoring transmission, designing, implementing, and evaluating HIV intervention strategies. In paper I, we used a total of 1276 HIV-1 subtype C pol sequences and employed state-of-art phylogenetic and phylodynamic tools to describe the molecular epidemiology of HIV in Ethiopia. LÄS MER