Sökning: "transient viremia"

Hittade 4 avhandlingar innehållade orden transient viremia.

  1. 1. Antiretroviral treatment of HIV-1 in Sweden with focus on virological aspects

    Författare :Erik Sörstedt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; antiretroviral therapy; transient viremia; viral blip; nucleoside transcriptase inhibitor resistance; dolutegravir; baseline viral load; HIV RNA; virological failure;

    Sammanfattning : From a clinical standpoint, there are many factors to consider when optimizing the care for people living with HIV (PLWH). With help from clinical guidelines, most obstacles can be addressed. Expanded knowledge is however in constant demand, from local conditions to universal processes. LÄS MER

  3. 2. On HIV-1 latency and viral reservoirs

    Författare :Tomas Mellberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; Latency; Intravenous immunoglobulin; residual viremia; low level viremia; Ultrasensitive PCR methods; Central nervous system;

    Sammanfattning : HIV-1 establishes a latent infection that is inaccessible to treatment in cellular and anatomical reservoirs. This thesis concerns several problematic issues of HIV-1 persistence, including ways to measure and monitor both the virus at low viral concentrations and the depletion of the reservoir. LÄS MER

  4. 3. Immune modulation in chronic HBV and HCV infection

    Författare :Catharina Hultgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HBV; HBeAg; HCV; NS3; chronic infection; humoral cellular immune response; Th1 Th2 cells; proliferative response;

    Sammanfattning : Chronic viral hepatitis is a major health problem worldwide. The two major viral causes for chronic hepatitis are the hepatitis B (HBV) and C viruses (HCV). HBV is a DNA virus with a rather limited genetic variability whereas HCV is an RNA virus with a high genetic variability. LÄS MER

  5. 4. Studies on Potency and breadth of HIV-1, HIV-2 and SIV neutralizing antibody responses

    Författare :Gülsen Özkaya Sahin; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV-2; SIV; envelope; neutralizing antibody; breadth; potency; IgG; IgA; complement; antibody-dependent complement-mediated inactivation; virus evolution; diversity; divergence;

    Sammanfattning : Even though the relative contribution of neutralizing antibodies (Nab) to prevent progression to AIDS during HIV-1 infection is still unclear, the induction of broadly NAb directed against HIV-1 through vaccination is considered to represent an important goal for the development of HIV-1 vaccines. Factors contributing to the induction of NAb may include the strength and duration of antigenic stimulation, the preservation of CD4+ T and B cells, the conformation of the HIV-1 envelope glycoprotein complex (Env), and the evolution of Env during infection. LÄS MER