Sökning: "E6 variant"

Hittade 5 avhandlingar innehållade orden E6 variant.

  1. 1. Genetic Risk Factors for Cervical Carcinoma in situ

    Författare :Anna Beskow; Peter L Stern; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Cervical carcinoma; human papillomavirus; viral load; long-term infection; HLA class II; p53; E6 variant; Genetik; Clinical genetics; Klinisk genetik; Medical Genetics; medicinsk genetik;

    Sammanfattning : Oncogenic human papillomaviruses (HPVs) are implicated in 99.7 % of cervical cancer cases but require the co-operation of other factors. To investigate potential genetic risk factors we have typed the HLA class II DRB1 and DQB1 loci in 478 women diagnosed with cervical carcinoma in situ and in 608 age-matched controls. LÄS MER

  3. 2. The role of human papillomavirus in adenocarcinoma of the uterine cervix

    Författare :Sonia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervix; Adenocarcinoma; HPV; Prevalence; Age; PCR; DNA-sequencing; p53; HPV16 - E6 gene - polymorphism;

    Sammanfattning : Background: Cervical carcinoma is the third most common malignant disease in women worldwide. The absolute frequency of adenocarcinoma of cervix uteri has increased during the last decade and accounts for about 15-20% of invasive cervical cancers. LÄS MER

  4. 3. Molecular biological techniques as a tool in diagnostic pathology : Applications in B-cell lymphoproliferative disease, medullary thyroid carcinoma and cervical carcinoma

    Författare :Mansour Alemi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; PCR-SSCP; MTC; RET mutation; Lymphoma; HPV; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Identification of malignancy associated with mutations in gene sequences requires detection ofas little as a single base difference. A powerful technique in mutation detection is polymerasechain reaction (PCR) followed by single-strand conformational polymorphism (SSCP) andsequencing. LÄS MER

  5. 4. Studies on human papillomavirus and molecular markers in head-neck cancer

    Författare :Cecilia Nordfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Oropharyngeal squamous cell carcinoma (OSCC), where tonsillar and base of tongue cancer (TSCC and BOTSCC) dominate, is associated with smoking and alcohol as well as human papillomavirus (HPV) infection. The incidence of TSCC and BOTSCC, has increased lately, mainly due to HPV infection. LÄS MER

  7. 5. Occurrence of human papillomaviruses (HPV) types in HPV related cancer and in the genital and oral tracts of young adults

    Författare :Juan Du; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human papillomavirus (HPV) is associated to cancer of the uterine cervix, the third most common cancer among women, but also to head and neck squamous cell carcinoma (HNSCC), the sixth most common type of cancer in the world. HPV occurs in most cervical cancer (CC). LÄS MER