Sökning: "trypanosomiasis"
Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet trypanosomiasis.
1. Novel treatment of African trypanosomiasis
Sammanfattning : Human African Trypanosomiasis (HAT) or Sleeping Sickness is fatal if untreated. Current drugs used for the treatment of HAT have difficult treatment regimens and unacceptable toxicity related issues. LÄS MER
2. Microfluidic Cell and Particle Sorting using Deterministic Lateral Displacement
Sammanfattning : Microfluidics is a field which has the potential to revolutionize medical diagnostics. The ability to sort and analyse cells by the use of portable handheld devices has the potential to enable sensitive devices for point-of-care diagnostics. LÄS MER
3. Salvage and de novo synthesis of nucleotides in Trypanosoma brucei and mammalian cells
Sammanfattning : All living cells are dependent on nucleic acids for their survival. The genetic information stored in DNA is translated into functional proteins via a messenger molecule, the ribonucleic acid (RNA). Since DNA and RNA can be considered as polymers of nucleotides (NTPs), balanced pools of NTPs are crucial to nucleic acid synthesis and repair. LÄS MER
4. Immunopathology and signalling molecules involved during experimental African trypanosomiasis
Sammanfattning : In humans, African trypanosomiasis occurs in two forms; the chronic West African form is caused by T.b. gambiense and the acute or subacute East African form is caused by T.b. LÄS MER
5. Oral eflornithine treatment of late-stage human African trypanosomiasis
Sammanfattning : Human African trypanosomiasis is a fatal disease unless treated. It is a parasitic vector borne disease endemic in sub-Saharan African countries. Eflornithine is a recommended treatment for gambiense human African trypanosomiasis (g-HAT) in the later disease stage when the parasites have infected the central nervous system. LÄS MER
