Sökning: "African Trypanosomiasis"
Visar resultat 1 - 5 av 15 avhandlingar innehållade orden African Trypanosomiasis.
1. Novel treatment of African trypanosomiasis
Sammanfattning : Human African Trypanosomiasis (HAT) or Sleeping Sickness is fatal if untreated. Current drugs used for the treatment of HAT have difficult treatment regimens and unacceptable toxicity related issues. LÄS MER
2. Salvage and de novo synthesis of nucleotides in Trypanosoma brucei and mammalian cells
Sammanfattning : All living cells are dependent on nucleic acids for their survival. The genetic information stored in DNA is translated into functional proteins via a messenger molecule, the ribonucleic acid (RNA). Since DNA and RNA can be considered as polymers of nucleotides (NTPs), balanced pools of NTPs are crucial to nucleic acid synthesis and repair. LÄS MER
3. Immunopathology and signalling molecules involved during experimental African trypanosomiasis
Sammanfattning : In humans, African trypanosomiasis occurs in two forms; the chronic West African form is caused by T.b. gambiense and the acute or subacute East African form is caused by T.b. LÄS MER
4. Oral eflornithine treatment of late-stage human African trypanosomiasis
Sammanfattning : Human African trypanosomiasis is a fatal disease unless treated. It is a parasitic vector borne disease endemic in sub-Saharan African countries. Eflornithine is a recommended treatment for gambiense human African trypanosomiasis (g-HAT) in the later disease stage when the parasites have infected the central nervous system. LÄS MER
5. Parasite signalling and host responses in experimental and human African trypanosomiasis
Sammanfattning : African trypanosomiasis or sleeping sickness is a disease of tropical Africa caused by the unicellular-flagellated protozoan parasite, Trypanosoma brucei (T b.), which is transmitted by its insect vector, the tsetse fly. In humans, there are two forms of the disease: a chronic form in West and Central Africa, caused by T. b. LÄS MER
