Sökning: "trigger mechanisms"

Visar resultat 16 - 20 av 179 avhandlingar innehållade orden trigger mechanisms.

1. 16. Mechanisms of malignant and non-malignant angiogenesis using zebrafish models

   Författare :Lasse Dahl Ejby Jensen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Pathological angiogenesis significantly contribute to the onset, development and progression of most common and severe human diseases including cancer, metastatic disease, cardiovascular disease, age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity. Under these pathological conditions, tissue hypoxia often acts as a trigger to switch on angiogenesis. LÄS MER

3. 17. Caspase activation in human neuroblastoma cells: mechanisms and spatiotemporal aspects

   Författare :Elena V. Ivanova; Kerstin Iverfeldt; Boris Zhivotovsky; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; apoptosis; caspase; local caspase activation; neurodegeneration; tau-anchored FRET sensors; tAFS; cancer; neuroblastoma; TNF-related apoptosis inducing ligand; TRAIL; protein kinase C; PKC; X-linked inhibitor of apoptosis protein; XIAP; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : Apoptosis is one of the modes of programmed cell death, in which several members of the caspase family of proteases play the central role. However, activation of apoptotic caspases does not necessarily lead to cell death. LÄS MER

4. 18. Role of Neutrophils and Innate Immune Mechanisms in Urinary Tract Infections

   Författare :Björn Frendéus; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Mucosal immunology; Infection Resistance; Neutrophils; Toll-like receptors; Urinary Tract Infections; Chemokine receptors; bakteriologi; virologi; mykologi;

   Sammanfattning : Urinary tract infections (UTI) are among the most common infections in man. Despite their prevalence, information on the molecular mechanisms defects that explain the increased susceptibility to disease are lacking. LÄS MER

5. 19. Impact of Mycobacterium tuberculosis and HIV-1 on innate immune mechanisms

   Författare :Jolanta Mazurek; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Human immunodeficiency virus type 1 (HIV-1), a causative agent of acquired immunodeficiency syndrome (AIDS), and Mycobacterium tuberculosis (Mtb), a causative agent of tuberculosis (TB), are among the leading causes of death from infectious disease worldwide. Interplay between HIV-1 and Mtb leads to the detrimental dysregulation of immune system mechanisms, which provides the conditions facilitating progression of the disease in co-infected individuals. LÄS MER

7. 20. Nutritional effects of barley products — Mechanisms of action in the intestinal tract

   Författare :Yadong Zhong; Kemicentrum Centrum för preventiv livsmedelsforskning; []
   Nyckelord :dietary fibre; malting; probiotics; high-fat diets; short-chain fatty acids; gut microbiota; low-grade inflammation; gene expression; Barley;

   Sammanfattning : Barley is one of the most important crops in the world. Although it is mainly used as the raw material for the production of beer and animal feed, it has recently attracted interest from nutritionists and consumers, due to its high content of dietary fibre, especially β-glucan, and its relation to various positive health effects. LÄS MER