Sökning: "trigger mechanisms"

Visar resultat 21 - 25 av 179 avhandlingar innehållade orden trigger mechanisms.

  1. 21. Apoptotic signaling in lung carcinoma cells : with focus on mechanisms of radioresistance

    Författare :Jessica Ekedahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In this thesis, IR-induced apoptotic signaling was studied in a panel of lung carcinoma cell lines. The goal was not only to achieve a better understanding of the process, but also to identify possible targets for pharmacological modulation to enhance the efficiency of radiotherapy. LÄS MER

  3. 22. The functional role of the lateral olivocochlear system and mechanisms underlying sound condtioning

    Författare :Xianzhi Niu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cochlea; dopamine; tyrosine hydroxylase; sound conditioning; apoptosis; acoustic trauma; lateral olivocochlear nucleus; D1 receptor; efferents;

    Sammanfattning : Sound conditioning is a process induced by a low-level, non-damaging acoustic stimulus that provides protection against subsequent detrimental forms of acoustic trauma. Many hypotheses have been advanced to explain the effect of sound conditioning, but the mechanisms underlying this phenomenon are still not yet known. LÄS MER

  4. 23. Signalomics : unsupervised and global strategies to explore mechanisms of radioresistence in lung cancer cells

    Författare :Sara Ståhl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To combat lung cancer (LC) which is the number one cancer associated killer, a combination of surgery, chemotherapy, radiotherapy and targeted agents are currently used. The main subtype of LC, Non small cell lung cancer (NSCLC) unfortunately responds poorly to conventional radiotherapy (RT) for reasons yet only partly understood. LÄS MER

  5. 24. Pathophysiological mechanisms and clinical manifestations in primary Sjögren’s syndrome and Systemic lupus erythematosus (SLE)

    Författare :Marika Kvarnström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary Sjögren’s syndrome (pSS) is a systemic inflammatory autoimmune condition. The etiology of pSS is mainly unknown, but it has been suggested that environmental factors trigger an immune response in genetically susceptible individuals. LÄS MER

  7. 25. Designing Electricity Distribution Network Charges for an Efficient Integration of Distributed Energy Resources and Customer Response

    Författare :Ibtihal Abdelmotteleb; Tómas Gómez; Javier Reneses; Rafael Cossent Árin; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; customer response; distributed energy resources; distribution network charges; local flexibility mechanisms; Electrical Engineering; Elektro- och systemteknik;

    Sammanfattning : A significant transformation has been gradually taking place within the energy sector, mainly as a result of energy policies targeting environmental objectives. Consequently, the penetration of Distributed Energy Resources (DERs) has been escalating, including self-generation, demand side management, storage, and electrical vehicles. LÄS MER