Sökning: "taurine"

Visar resultat 11 - 15 av 30 avhandlingar innehållade ordet taurine.

  1. 11. Functional characterization of a peroxisomal acyltransferase gene family

    Författare :Sarah-Jayne Reilly; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Peroxisomes are cell organelles that play an important role in the metabolism of a variety of lipids including very long chain fatty acids, dicarboxylic acids, bile acids, and xenobiotic carboxylic acids. The metabolism of lipids in peroxisomes requires the concerted efforts of many different enzymes, which includes members of the type I acyl-CoA thioesterase/acyltransferase protein family and the nudix hydrolases. LÄS MER

  3. 12. Brain glycine receptors as a common target for alcohol and the relapse-preventing drug acamprosate - a preclinical study

    Författare :Pei Pei Chau; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alcoholism; Acamprosate; Glycine receptor; Preclinical study; Dopamine; Ethanol;

    Sammanfattning : Alcohol abuse and dependence make up the most prevalent categories of substance use disorders in the world. Converging evidence from the current research group has identified two receptor populations, the glycine (GlyRs) and nicotinic acetylcholine receptors (nAChRs) in the mesolimbic dopamine system, as two potentially important targets for the development of new medication to treat alcohol dependence. LÄS MER

  4. 13. Profiling Plasma Metabolite Alterations in Diet-Induced Obesity and Diabetes Using NMR Metabolomics

    Författare :João Vieira; Diabetes och hjärnans funktion; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolite profiling; diet-induced obesity; type 2 diabetes mellitus; 1H-NMR spectroscopy; metabolism alterations; post-stroke recovery;

    Sammanfattning : Diets rich in saturated fat and sedentary lifestyles markedly contribute to obesity and metabolic syndrome-related diseases, including type 2 diabetes mellitus (T2D). Metabolite profiling plays a pivotal role in understanding these metabolic diseases. LÄS MER

  5. 14. Studies of bioactive lipids in cancer

    Författare :Vicky Chatzakos; Petra De Verdier; Jenny Flygare; Åke Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; Sphingolipids; N-acyl amino acids; cancer; molekylärgenetik; Molecular Genetics;

    Sammanfattning : Lipids are a broad class of molecules that, besides being a major form of energy storage and components of cell membranes, act as bioactive signalling molecules. N-acyl taurines are structurally related to endocannabinoids that are known to exert antiproliferative actions in a variety of cancer cells. LÄS MER

  7. 15. Genomic variation across European cattle: contribution of gene flow

    Författare :Maulik Upadhyay; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : European cattle display vast phenotypic diversity which can be attributed to genomic variation such as single nucleotide polymorphisms (SNPs) and structural variations (SVs).The distribution of these genomic variations in a population is heavily in uenced by different population genomic forces. LÄS MER