Sökning: "tRNA and non-coding RNA"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden tRNA and non-coding RNA.

1. 1. Mediator and its role in non-coding RNA and chromatin regualtion

   Författare :Jonas O P Carlsten; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mediator; transcription; centromere; telomere; tRNA; exosome;

   Sammanfattning : Mediator is a multiprotein complex required for the regulation of RNA Polymerase II (Pol II) transcription. Mediator transmits regulatory signals from activators and repressors to the Pol II machinery at the promoter, but the complex has also many other functions related to control of gene transcription. LÄS MER

3. 2. Comparative genomics of the genus Mycobacterium : Genome evolution, phylogeny and diversity

   Författare :Phani Rama Krishna Behra; Leif Kirsebom; Bengt Persson; Mikael Rhen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mycobacterial genomes; core gene phylogeny; tRNA and non-coding RNA; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

   Sammanfattning : The genus Mycobacterium includes more than 190 species, and many cause severe diseases such as tuberculosis and leprosy. According to the "World Health Organization", in year 2019 alone, 10 million people developed TB, and 1.4 million died. LÄS MER

4. 3. All Roads Lead to the Non-Coding RNome : Evolution of Multicellularity and Host Response to Bacterial Infection

   Författare :Jonas Kjellin; Fredrik Söderbom; Jonathan Chubb; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ncRNA; Dictyostelia; miRNA; Class I RNA; host-pathogen interaction; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

   Sammanfattning : The ability to control gene expression is fundamental for all living organisms. Therefore, a large variety of regulatory mechanisms exist in each cell which are essential for e.g. developmental processes and to quickly adapt to different cellular stresses such as infection. LÄS MER

5. 4. Post-transcriptional control of stem and cancer cell fate. New roles for an old RNA modification

   Författare :Nicola Guzzi; Avdelningen för molekylär hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA modifications; pseudouridine; translational control; Stem cells; tRNA-derived fragments; MDS;

   Sammanfattning : Recent advances in high-throughput sequencing technologies uncovered widespread RNA modifications on coding and non-coding RNAs collectively refer to as the epitranscriptome. However, we are only now starting to appreciate the impact of the epitranscriptome in regulating cell biology. LÄS MER

7. 5. Size matters : RNA silencing processes in Phytophthora infestans

   Författare :Anna Åsman; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Non-coding RNAs do not encode proteins but instead function through their own RNA sequence. These molecules range from several thousands of nucleotides (nt) in length down to around 20 nt. Specifically, small RNAs (sRNAs) have critical functions in eukaryotic cells, despite being only 20-30 nt long. LÄS MER