Sökning: "ncRNA"

Visar resultat 1 - 5 av 15 avhandlingar innehållade ordet ncRNA.

  1. 1. Computational Approaches to the Identification and Characterization of Non-Coding RNA Genes

    Författare :Pontus Larsson; Anders Virtanen; Leif Kirsebom; Stephen Mount; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ncRNA; snRNA; U1; splice site; alternative splicing; Dictyostelium; nucleotide composition; partial sums; Bioinformatics; Bioinformatik;

    Sammanfattning : Non-coding RNAs (ncRNAs) have emerged as highly diverse and powerful key players in the cell, the range of capabilities spanning from catalyzing essential processes in all living organisms, e.g. protein synthesis, to being highly specific regulators of gene expression. LÄS MER

  3. 2. All Roads Lead to the Non-Coding RNome : Evolution of Multicellularity and Host Response to Bacterial Infection

    Författare :Jonas Kjellin; Fredrik Söderbom; Jonathan Chubb; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ncRNA; Dictyostelia; miRNA; Class I RNA; host-pathogen interaction; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : The ability to control gene expression is fundamental for all living organisms. Therefore, a large variety of regulatory mechanisms exist in each cell which are essential for e.g. developmental processes and to quickly adapt to different cellular stresses such as infection. LÄS MER

  4. 3. Understanding the Noise : Spliceosomal snRNA Profiling

    Författare :Lei Liu Conze; Anders Virtanen; Lars Wieslander; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ncRNA; snRNA; U1; splice site; alternative splicing; high-throughput sequencing; 454; SNP; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : The concept of the gene has been constantly challenged by new discoveries in the life sciences. Recent challenging observations include the high frequency of alternative splicing events and the common transcription of non-protein-coding-RNAs (ncRNAs) from the genome. The latter has long been considered noise in biological systems. LÄS MER

  5. 4. Regulatory roles of two small RNAs in the human pathogen Listeria monocytogenes and the evaluation of an alternative infection model

    Författare :Jonas Gripenland; Jörgen Johansson; Tom Geissmann; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; small RNA; sRNA; Riboswitch; Listeria monocytogenes; ncRNA; PrfA; molekylärbiologi; Molecular Biology;

    Sammanfattning : Listeriosis is a potentially lethal disease caused by the Gram-positive facultative intracellular pathogen Listeria monocytogenes (L.m.). L. LÄS MER

  7. 5. Computational identification of non-coding RNAs

    Författare :Paul Piccinelli; Göteborgs universitet; []
    Nyckelord :RNase P; RNase MRP; IRE; non-coding RNA; secondary structure;

    Sammanfattning : A large amount of genomic information is now becoming available. Suitable bioinformatic tools to organize and analyze this vast amount of information are therefore important. In the case of protein genes, the majority of these may be correctly identified using standard search methods that are based on sequence alignment. LÄS MER