Sökning: "ribavirin"

Visar resultat 11 - 15 av 24 avhandlingar innehållade ordet ribavirin.

  1. 11. Hepatitis C virus infection in patients receiving opiate substitution therapy in Sweden

    Författare :Anna Jerkeman; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The hepatitis C virus (HCV) is a blood borne virus effectively spread through injection practices. Consequently, people who inject drugs (PWID) are at the center of the current HCV epidemic in industrialized countries, with regards both to prevalence and incidence. LÄS MER

  3. 12. Infections in allogeneic stem cell transplanted patients : clinical and immunological aspects

    Författare :Elda Sparrelid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HSCT; bacteraemia invasive fungal infection; interstitial pneumonia; immunity.;

    Sammanfattning : In allogeneic haematopoietic stem cell transplantation (HSCT), 30 to 40 % of transplant related mortality is associated with infection complications. This includes invasive bacterial and fungal infection, and interstitial pneumonia (IP), which are two important causes of morbidity and mortality. LÄS MER

  4. 13. Discovery and evaluation of direct acting antivirals against hepatitis C virus

    Författare :Eldar Abdurakhmanov; Helena Danielson; David Frick; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Direct acting antivirals; Hepatitis C; NS3-4A protease; NS5B polymerase; structure-based drug discovery; fragment-based drug discovery; surface plasmon resonance; Biokemi; Biochemistry;

    Sammanfattning : Until recently, the standard therapy for hepatitis C treatment has been interferon and ribavirin. Such treatment has only 50% efficacy and is not well tolerated. The emergence of new drugs has increased the treatment efficacy to 90%. LÄS MER

  5. 14. Immunoregulation by mononuclear phagocytes. Mechanisms and clinical implications

    Författare :Ana Romero; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : The cytotoxic effector lymphocytes of the immune system, the natural killer (NK) cells and the CD8+ T lymphocytes (CTL), have been ascribed a pivotal role in defense against malignancy. However, the function of these cells is frequently compromised, in particular at sites of malignant cell expansion. LÄS MER

  7. 15. Combination chemotherapy for human immunodeficiency virus infection

    Författare :Sarah Palmer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The worldwide spread of human immunodeficiency virus (HIV) has spurred the search for effective drugs to combat this deadly virus. The limited effect of monotherapy treatment, in large measure due to the development of drug resistant viral strains, has led to increased emphasis on combination chemotherapy for the treatment of HIV, the focus of this study. LÄS MER