Sökning: "randomized clinical trial"

Visar resultat 1 - 5 av 457 avhandlingar innehållade orden randomized clinical trial.

  1. 1. Localized Prostate Cancer : Results From a Randomized Clinical Trial

    Författare :Anna Bill-Axelson; Lars Holmberg; Bo Johan Norlén; Peter Wiklund; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; prostate cancer; localized; randomized; biopsies; interviews; Kirurgi; Surgery; Kirurgi;

    Sammanfattning : The aims of the thesis were to• explore whether radical prostatectomy is beneficial compared with watchful waiting in survival and disease progression• find possible effect modifiers• evaluate a protocol of multiple biopsies and investigate if men with previous benign prostate biopsies are a group at risk for later prostate cancer• inquire into patients’ and clinicians’ experiences of randomization in order to find out what made this study possible to conduct, and thereby contribute to improve randomization in the futureThe background material was a large randomized clinical trial, the Scandinavian Prostatic Cancer Group Study Number 4, or SPCG-4, which was open for inclusion from February 1989 through December 1999. It comprised 695 men in Sweden, Finland and Iceland who had localized prostate cancer and were randomized to either radical prostatectomy or watchful waiting. LÄS MER

  2. 2. Trauma-focused digital support, momentary psychological states, and long-term symptoms : Randomized controlled trial and ecological momentary assessment

    Författare :Ida Hensler; Filip Arnberg; Josefin Sveen; Martin Cernvall; Monique Pfaltz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; mHealth; telemental health; app; PTSD Coach; trauma; potentially traumatic event; posttraumatic stress; PTSD; self-rated health; ecological momentary assessment; randomized controlled trial; COVID-19; pandemic; e-hälsa; digital hälsa; internetbehandling; app; PTSD Coach; trauma; posttraumatisk stress; PTSD; självskattad hälsa; COVID-19; pandemi; Psychiatry; Psykiatri; Psychology; Psykologi;

    Sammanfattning : Perceived health, symptoms, and emotional states may fluctuate in response to coping efforts and support. The short- and long-term effects, benefits, and harms of trauma-focused self-management apps should be investigated. LÄS MER

  3. 3. Complementary and alternative medicine in cancer : from utilization to a randomized controlled trial

    Författare :Kathrin Wode; Per Fransson; Roger Henriksson; Lena Sharp; Johanna Hök Nordberg; Vinjar Magne Fønnebø; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; epidemiology; evidence-based medicine; neoplasms; pancreatic neoplasms; adult; integrative oncology; complementary therapies; treatment refusal; communication; physician-patient relations; mistletoe; palliative care; quality of life; cross-sectional studies; qualitative research; randomized controlled trial; Sweden; Europe; medicin; Medicine;

    Sammanfattning : Background: Complementary and alternative medicine (CAM) are non-conventional health care approaches used in parallel with or instead of conventional medicine. Little is known about Swedish patients’ patterns of complementary CAM use in the context of cancer. LÄS MER

  4. 4. Depression in teenagers and young adults : foundational studies of the new treatment paradigm TARA: Training for Awareness, Resilience, and Action

    Författare :Erik Ekbäck; Eva Henje Blom; Ida Blomqvist; Jenny Molin; Inga Dennhag; Thorbjörn Lundberg; Elizabeth McCauley; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; adolescents; young adults; medical students; mental health; anxiety; psychological stress; qualitative research; randomization; yoga; mindfulness; psychotherapy; antidepressant drugs; biomarkers; clinical trial; feasibility studies; online intervention; reliability; validity; confirmatory factor analysis; measurement invariance; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Sammanfattning : Introduction: Depression in adolescents and young adults is an increasing global health concern and available treatments are not convincingly effective. It is therefore important to develop and test novel treatments to improve treatment outcomes. LÄS MER

  5. 5. Anorexia nervosa - The journey towards recovery : A randomized controlled treatment trial: assessment, prediction, treatment outcome and clinical change

    Författare :Erika Nyman-Carlsson; Lauri Nevonen; Ingemar Engström; Sanna Aila Gustafsson; Øivind Rø; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anorexia nervosa; young adults; randomized controlled trial; outpatient psychotherapy; treatment outcome; predictors; recovery;

    Sammanfattning : The overall aim of this thesis was to study young adult women with anorexia nervosa (AN) participating in an randomized controlled trial in relation to assessment, treatment outcome, prediction, and clinical change. The results confirm the Eating Disorder Inventory-3 as a valid instrument for measuring eating disorder symptoms and general psychopathology. LÄS MER