Sökning: "preference stability"

Visar resultat 6 - 10 av 41 avhandlingar innehållade orden preference stability.

  1. 6. Nucleic Acids as Drugs and Drug Targets With Focus on Anticancer Active Platinum Complexes and Small Interfering RNAs

    Författare :Hanna Hedman; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Anticancer drugs; platinum complexes; cisplatin; oxaliplatin; nucleic acid; RNA; DNA; siRNA; thermodynamic stability; mass spectrometry; MALDI-MS; chemical probing; luciferase assay;

    Sammanfattning : To ensure that patients receive a safe and effective treatment, it is important to understand how drugs interact with and affect molecules within a cell. Here, evaluation of platinum based drugs and their ability to interfere with nucleic acid functions is presented. LÄS MER

  3. 7. Long-term Environmental Problems, Economic Measures and Physical Indicators

    Författare :Christian Azar; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; stability analysis; discounting; environmental debt; sustainability; intergenerational; weight factors; population dynamics; the greenhouse effect; economics; indicators;

    Sammanfattning : This thesis consists of five papers and an introduction dealing with various aspects of the use of environmental resources. In both Paper I, The marginal cost of CO2 emissions, and Paper II, Discounting and distributional considerations in the context of global warming, we analyse the economics of the greenhouse effect. LÄS MER

  4. 8. Structural Studies of Binding Proteins: Investigations of Flexibility, Specificity and Stability

    Författare :Ulrika Magnusson; Sherry L. Mowbray; Anthony J. Wikinson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Periplasmic binding protein; X-ray crystallography; conformational change; acidophile; protein specificity; protein structure; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Sammanfattning : Binding proteins are present both in gram-negative and gram-positive bacteria. They are the recognition components of the ABC transport systems that transport different nutrients into the cell, and are in some cases also involved in chemotaxis. LÄS MER

  5. 9. From health outcomes to value assessments : preference-based evaluation of interventions and valuation of productivity costs among working adults

    Författare :Emmanuel Aboagye; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: This thesis applies value assessment frameworks to non-specific low back pain (LBP) in a working population to evaluate health outcomes and to estimate productivity costs. LBP is a common diagnosis in primary health care. LÄS MER

  7. 10. Evolution and control of the three dimensional functional microstructure of Polymer:Fullerene photovoltaic blends

    Författare :Olof Bäcke; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; crosslinking; fullerene crystals; tomography; transmission electron mi- croscopy; organic solar cell; in situ; polymer:fullerene film; thermal degradation;

    Sammanfattning : Polymer:fullerene bulk-heterojunction thin films show great promise for use as active layers in organic solar cells. However, their low thermal stability is a hindrance that complicates the manufacturing and influences the lifetime of devices. LÄS MER