Sökning: "perivascular spaces"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden perivascular spaces.

  1. 1. Cerebral arterial pulsatility imaging using 4D flow MRI : methodological development and applications in brain aging

    Författare :Tomas Vikner; Anders Wåhlin; Anders Eklund; Jan Malm; Lars Nyberg; Susanne Schnell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; 4D flow MRI; medical image analysis; cerebral hemodynamics; arterial pulsatility; DCE MRI; blood-brain barrier; white matter lesions; perivascular spaces; cerebral small vessel disease; hippocampus; cognition; aging; biomedicinsk strålningsvetenskap; Biomedical Radiation Science;

    Sammanfattning : 4D flow magnetic resonance imaging (MRI) is increasingly recognizedas a versatile tool to assess arterial and venous hemodynamics. Cerebral arterial pulsatility is typically assessed by analyzing flow waveforms over the cardiac cycle, where flow amplitude is a function of cardiac output, central arterial stiffness, and cerebrovascular resistance and compliance. LÄS MER

  3. 2. Microvascular disease in cognitive impairment

    Författare :Mana Shams; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cerebral small vessel disease has been recognized as the greatest vascular contributor to dementia. Previously, small vessel disease was thought to be part of normal aging. LÄS MER

  4. 3. Modelling, Simulaltion, and Visualization of Deep Brain Stimulation

    Författare :Mattias Åström; Karin Wårdell; Göran Salerud; Stig Rehncrona; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Deep brain stimulation (DBS) is an effective surgical treatment for neurological diseases such as essential tremor, Parkinsonʹs disease (PD) and dystonia. DBS has so far been used in more than 70 000 patients with movement disorders, and is currently in trial for intractable Gilles de la Tourette’s syndrome, obsessive compulsive disorders, depression, and epilepsy. LÄS MER

  5. 4. Cardiovascular risk factor profiles in the development and progression of physical limitation in old age : a population-based study

    Författare :Emerald Georgiana Heiland; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Physical performance;

    Sammanfattning : Preservation of independence has been reported to be highly desired by older adults, even more than longevity. However, subclinical cardiovascular pathology can threaten a healthy older adult’s maintenance of physical function. LÄS MER

  7. 5. Developing a Porcine Model to Study the Glymphatic System

    Författare :Nicholas Bechet; Glia-Immune Interactions; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glymphatic system; cerebrospinal fluid; Porcine; in vivo imaging; amyloid beta; Alzheimer disease;

    Sammanfattning : The glymphatic system is a brain-wide solute clearance system that has developed in the brain to clear metabolic waste during sleep. This clearance is mediated by advective fluxes of cerebrospinal fluid (CSF) along perivascular spaces (PVS) and through the brain. LÄS MER