Sökning: "palladium-catalyzed reactions"

Visar resultat 21 - 25 av 49 avhandlingar innehållade orden palladium-catalyzed reactions.

  1. 21. Heck Reactions with Aryl Chlorides : Studies of Regio- and Stereoselectivity

    Författare :Gopal K. Datta; Mats Larhed; Anders Hallberg; Martin Oestreich; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heck reaction; aryl chloride; vinyl ether; regioselective; stereoselective; palladium; chelation control; microwave; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Homogeneous palladium-catalyzed Heck vinylation of aryl chlorides was investigated under air using Herrmann’s palladacycle and the P(t-Bu)3-liberating salt [(t-Bu)3PH]BF4. Based on the results, controlled microwave heating was utilized to accelerate model Heck reactions with aryl chlorides down to 30 min employing an electron-poor olefin and a mixture of an ionic liquid and 1,4-dioxane as solvent. LÄS MER

  3. 22. Selectivity in Palladium- and Enzyme-Catalyzed Reactions : Focusing on Enhancement of Reactivity

    Författare :Peter Nilsson; Anders Hallberg; Mats Larhed; Matthias Beller; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Palladium; Heck; PCR; Microwaves; Farmaceutisk kemi; Pharmaceutical chemistry; Farmaceutisk kemi;

    Sammanfattning : Catalysis has a profound impact on all living species on the earth. Nature’s catalysts, the enzymes, have the ability to selectively promote a specific bio-chemical transformation, given the required substrate. LÄS MER

  4. 23. MECHANISTIC INVESTIGATIONS OF TRANSITION METAL CATALYZED REACTIONS

    Författare :Jonatan Kleimark; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; alkene insertion; allylic alkylation; catalysis; cross coupling; density funtional theory; free energy surface; iron; kinetic investigation; Mizoroki-Heck reaction; nickel; palladium; reaction mechanism; sulfinylation; transition metal;

    Sammanfattning : Transition metal catalyzed reactions have had a large impact on the human progress for the last century. Several extremely important areas, such as the agricultural industry and the plastic industry, have benefited from this development. LÄS MER

  5. 24. Iron-Catalyzed Reactions and X-Ray Absorption Spectroscopic Studies of Palladium- and Ruthenium-Catalyzed Reactions

    Författare :Arnar Guðmundsson; Jan-Erling Bäckvall; Hans-Joachim Knölker; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Iron; XAS; Cycloisomerization; DKR; Oxidation; organisk kemi; Organic Chemistry;

    Sammanfattning : The focus of this thesis is twofold: The first is on the application of iron catalysis for organic transformations. The second is on the use of in situ X-ray absorption spectroscopy (XAS) to investigate the mechanisms of a heterogeneous palladium-catalyzed reaction and a homogeneous ruthenium-catalyzed reaction. LÄS MER

  7. 25. GALIELLALACTONE ANALOGUES – SYNTHESIS AND PROPERTIES

    Författare :Ritha Gidlöf; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galiellalactone; one-pot peptide coupling and intramolecular Michael addition; tandem palladium-catalyzed carbonylation intramolecular Diels-Alder; STAT3 inhibition;

    Sammanfattning : Cancer cells use normal cell signalling pathways in a proliferative fashion in order to prolong their own survival. Inhibition of one of the major signal proteins, STAT3 (Signal Transducer and Activator of Transcription 3) has previously been shown to induce apoptosis. LÄS MER