Sökning: "neutralizing"

Visar resultat 6 - 10 av 163 avhandlingar innehållade ordet neutralizing.

  1. 6. In vivo evaluations of the neutralizing effect of a hydroxyl ion-releasing resin composite and a prophylactic gel on plaque acidogenicity : measured by the microtouch method

    Författare :Anitha Persson; Jan van Dijken; Peter Lingström; Anette Oliveby; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; caries; clinical; buffering; elderly; plaque pH; resin composite; restorations; microorganisms; ODONTOLOGY; ODONTOLOGI;

    Sammanfattning : The prevalence of dental caries has decreased dramatically in most developed countries since the sixties and the number of remaining teeth in adults has increased during the last decades. Elderly as a group will during aging become an increasing risk group for caries. LÄS MER

  2. 7. Exploring Anti-FVIII Antibodies in Haemophilia A - Role in In Vitro Haemostasis and Clinical Disease

    Författare :Jenny Klintman; Malmö Klinisk koagulationsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hemophilia A; inhibitors; non-neutralizing anti-FVIII antibodies; thrombin generation assay; ELISA;

    Sammanfattning : Haemophilia A (HA) is caused by defective synthesis of coagulation factor VIII(FVIII), which has serious effects on haemostasis; joints being the most common site of bleeding. The development of FVIII replacements has improved the situation for patients with haemophilia such that chronic arthropathy can be prevented, and life expectancy and the quality of life have increased. LÄS MER

  3. 8. HIV-induced humoral immune response with specific relevance to IgA

    Författare :Pia Skott; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; secretory lgA; neutralizing antibodies; mucosal immunity;

    Sammanfattning : Human Immunodeficiency Virus (HIV) transmission occurs primarily after hetero- and homosexual contact and across mucosal surfaces. The immune response in mucosal tissues is typified by secretory immunoglobulin A (SIgA), which is the predominant lg class in human external secretions. LÄS MER

  4. 9. Dendritic cell and IgA responses in SIV and HIV-1 pathogenesis

    Författare :Johan Söderlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DC; SIV; HIV-1; macaques; neutralizing antibodies; IgA;

    Sammanfattning : Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV-1) can infect different subsets of dendritic cells (DC). Such cells may therefore not only be involved in the generation of recruitment of naïve T and B lymphocytes in induction of SIV/HIV-1 specific adaptive responses but also transmit virus from port of entrance to the secondary lymphoid compartment generating systemic viral spread. LÄS MER

  5. 10. Receptor use of primate lentiviruses

    Författare :Dalma Vödrös; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; SIV; animal models; receptor use; neutralizing antibodies; CD4-independence;

    Sammanfattning : Human and simian immunodeficiency viruses (HIV and SIV) enter target cells using CD4, the primary cell surface receptor and a secondary receptor, called coreceptor. Coreceptor use of HIV can be related to other biological features of the virus and to the severity of infection as well. LÄS MER