Sökning: "neuroendocrine phenotype"
Visar resultat 1 - 5 av 18 avhandlingar innehållade orden neuroendocrine phenotype.
1. Vesicle proteins as markers for neuroendocrine tumors
Sammanfattning : The neuroendocrine (NE) tumours comprise a diversity of tumours which share commonproperties, e.g. the capacity to produce, store and release hormones. A prominent feature ofthe NE phenotype is the production of secretory granules with associated vescicle proteins,e. LÄS MER
2. Small intestinal neuroendocrine tumours - Disease models, tumour development, and remedy
Sammanfattning : Small intestinal neuroendocrine tumours (SINETs) are malignant neoplasms which at the time of diagnosis often present with distant metastasis. The field of SINET research faces several challenges. LÄS MER
3. Gastrointestinal stromal tumours. On diagnosis and treatment
Sammanfattning : Gastrointestinal stromal tumours (GIST) are thought to originate from the interstitial cells of Cajal, which show many properties in common with neurons of the gastrointestinal tract. High-risk GIST has a very poor prognosis and tumour recurrence is common after intentionally curative surgery. LÄS MER
4. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate
Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER
5. Zebrafish as a model to study the neuroendocrine system and toxicity of endocrine disruptors
Sammanfattning : Zebrafish is a popular vertebrate model system to study development and perform genetic analysis. It offers numerous advantages such as small size, short generation time, high fecundity, rapid and ex utero development of embryos and optically transparent embryos. LÄS MER