Sökning: "neuroblastoma"
Visar resultat 21 - 25 av 226 avhandlingar innehållade ordet neuroblastoma.
21. Hypoxia-induced phenotypic modulation of human neuroblastoma cells
Sammanfattning : Neuroblastoma is a childhood tumour derived from cells of the sympathetic nervous system, which are arrested at low differentiation stages. Low differentiation stage and high tumour stage correlate to poor outcome. LÄS MER
22. Hypoxic gene regulation and oncogenic pathways in neuroblastoma
Sammanfattning : Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. LÄS MER
23. Approaches to Treatment of Children with Advanced Neuroblastoma
Sammanfattning : Children with advanced neuroblastoma are at high risk for relapse of multidrug resistant disease, despite initial response to intensive multimodality treatment. Neuroblastomas have similarities with immature neuroblasts seen during embryonic development of the sympathetic nervous system (the origin of these tumors). LÄS MER
24. Effects of ellagic acid in human neuroblastoma cells
Sammanfattning : A diet rich in polyphenols has been proposed to have beneficial health effects and to reduce risk of disease. Ellagic acid, a polyphenol common in red berries and pomegranates, has potential anti-tumorigenic effects that make it interesting to further study in different cancer cell systems. LÄS MER
25. Notch Signaling in Neuroblastoma and Renal Cell Carcinoma
Sammanfattning : The Notch signaling pathway governs cell functions essential for normal development and organogenesis. Aberrant Notch signaling has been implicated in tumorigenesis by perturbing control of proliferation, differentiation, apoptosis, migration and angiogenesis. LÄS MER