Sökning: "monomer-dependent secondary nucleation"

Hittade 1 avhandling innehållade orden monomer-dependent secondary nucleation.

1. 1. α-Synuclein Fibril Formation and the Effects of Lipid Membranes

   Författare :Ricardo Gaspar; Fysikalisk kemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Protein misfolding; alpha-synuclein; Parkinson s disease; microscopic rate constants; Thioflavin T; ganglioside lipids; Exosomes; protein-lipid co-aggregation; model membranes; monomer-dependent secondary nucleation;

   Sammanfattning : Amyloid protein aggregation results in major disturbances of cellular processes in humans. The most common amyloid-related disorders are Alzheimer´s disease and Parkinson´s disease. Parkinson´s disease is charaterized by the formation of protein-rich aggregates that are deposited in neurons, termed Lewy bodies and Lewy neurites. LÄS MER