Sökning: "metabolomic"

Visar resultat 11 - 15 av 41 avhandlingar innehållade ordet metabolomic.

  1. 11. Combined profiling in aspen : a systems biology approach

    Författare :Ogonna Obudulu; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : This thesis presents efficient systems biology modelling strategies for integrating complex multi-platform datasets in order to increase our understanding of stress biology, wood formation and secondary cell wall formation in Populus trees and connected responses to perturbations in organisms, particularly aspen. It is based on studies reported in four appended papers, designated Papers I-IV. LÄS MER

  3. 12. Differentiation of renal oncocytoma from renal cell carcinoma by means of ⁹⁹Tc-Sestamibi SPECT/CT

    Författare :Antonios Tzortzakakis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Purpose: An increasing body of literature indicates the beneficial role of [99m]Tc-Sestamibi SPECT/CT in the non-invasive differentiation of renal oncocytoma (RO) from renal cell carcinoma (RCC). This thesis presents a comprehensive approach of [99m]Tc-Sestamibi SPECT/CT examination following the implementation of quantitative tools in addition to visual assessment. LÄS MER

  4. 13. The mechanism of HAMLET-induced cell death - cellular signalling, oncogenes and clinical perspectives

    Författare :Petter Storm; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HAMLET; cancer; cell death; c-Myc; glycolysis; hexokinase; ion channels; p38 MAPK; lipids; colon cancer; beta-catenin;

    Sammanfattning : Despite recent advances in cancer treatment, truly innovative approaches are required to move beyond the modest benefits achieved to date. HAMLET is a human protein-lipid complex originally discovered in breast milk able to kill a wide range of tumour cells while leaving healthy, differentiated cells unaffected. LÄS MER

  5. 14. Studies of plant interactions with other organisms to understand Bacillus mediated stress management

    Författare :Anna Johansson; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : The naturally evolved plant defense system is not always effective, due to adaptations among the attackers. Crop protective chemicals have many negative effects on the environment. Ecosystem services, like beneficial microorganisms, are of great interest for plant stress management in sustainable crop production. LÄS MER

  7. 15. Molecular epidemiology of complex heritable disease : applications in genomics and metabolomics

    Författare :Robert Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Modern high-throughput molecular technologies (collectively referred to as “omic” platforms) are generating unprecedented amounts of data on human variation. The four papers in this thesis each investigate and characterize associations between common, complex, heritable disease, and genetic or metabolomic markers from omic platforms. LÄS MER