Sökning: "lymphangiogenesis"

Visar resultat 6 - 10 av 20 avhandlingar innehållade ordet lymphangiogenesis.

  1. 6. Hem- and lymph-angiogenesis in cancer metastasis

    Författare :Hong Ji; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Angiogenesis, the process of sprouting new microvessels from the preexisting vasculature, is known to promote tumor growth. However, the role of tumor angiogenic vessels in facilitating metastasis remains poorly understood. LÄS MER

  3. 7. The role of VEGF family in angiogenesis, tumor growth and metastasis

    Författare :Xiaojuan Yang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. LÄS MER

  4. 8. Small-Molecule Galectin Ligands : Structure-Based Optimisation of Affinity and Selectivity

    Författare :Sjors Van Klaveren; Centrum för analys och syntes; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Galectins; structure activity relation;

    Sammanfattning : In the body, all cell surfaces are covered with glycans, and many regulatory components havecarbohydrates attached to them, which can aid in their function. Galectins are a family of proteins whichcan bind to specific glycans and oligosaccharides and cross-link them to influence a wide range of cellularprocesses. LÄS MER

  5. 9. Angiogenesis modulates obesity and insulin sensitivity

    Författare :Jennifer Honek; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Both white and brown fat are highly vascularized tissues and vascular functions in adipose tissues remain largely unknown. In this thesis work, we aimed to study blood vessels in modulation of adipose tissue functions under physiological conditions. LÄS MER

  7. 10. The elephant in the cell : A multifaceted undertaking to uncover the molecular principles behind lymphatic endothelial cell identity

    Författare :Virginia Panara; Katarzyna Koltowska; Taija Mäkinen; Marcel den Hoed; Sarah de Val; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lymphatic endothelium; Development; Epigenetic; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Sammanfattning : The lymphatic vascular network is composed of a series of blind ended vessels, and is involved in physiological functions such as fluid homeostasis, lipid metabolism and immune trafficking. Despite lymphatic endothelial cells being derived from multiple organs, they share common molecular denominators, including the expression of the transcription factor Prox1. LÄS MER