Sökning: "Katarzyna Koltowska"

Hittade 2 avhandlingar innehållade orden Katarzyna Koltowska.

  1. 1. The elephant in the cell : A multifaceted undertaking to uncover the molecular principles behind lymphatic endothelial cell identity

    Författare :Virginia Panara; Katarzyna Koltowska; Taija Mäkinen; Marcel den Hoed; Sarah de Val; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lymphatic endothelium; Development; Epigenetic; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Sammanfattning : The lymphatic vascular network is composed of a series of blind ended vessels, and is involved in physiological functions such as fluid homeostasis, lipid metabolism and immune trafficking. Despite lymphatic endothelial cells being derived from multiple organs, they share common molecular denominators, including the expression of the transcription factor Prox1. LÄS MER

  3. 2. From endothelial cells to the vascular network : How cell migration and proliferation are orchestrated to build lymphatic vessels

    Författare :Di Peng; Katarzyna Koltowska; Vermot Julien; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lymphangiogenesis; Cell migration; Zebrafish; Biologi med inriktning mot zoologisk utvecklingsbiologi; Biology with specialization in Animal Development;

    Sammanfattning : Lymphatic endothelial cells (LECs) migrate across body to form a branched network, which is crucial for fluid drainage and immune cell trafficking of the tissues. However, the molecular mechanisms behind the spatiotemporal regulation and fine-tuning of LEC migration remain largely unknown. LÄS MER