Sökning: "left ventricular fibrosis"

Visar resultat 1 - 5 av 13 avhandlingar innehållade orden left ventricular fibrosis.

1. 1. Mechanical and histological disturbances in advanced heart failure and cardiac transplantation

   Författare :Matteo Cameli; Michael Henein; Guy Lloyd; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Advanced heart failure; heart transplantation; speckle tracking echocardiography; left ventricular function; right ventricular function; left ventricular fibrosis; left ventricular filling pressure; atrial strain; kariologi; Cariology;

   Sammanfattning : The general purpose of this thesis is to establish capability and accuracy of speckle tracking echocardiography (STE) in assessing left atrial (LA), left ventricular (LV) and right ventricular (RV) function and their correlation with myocardial fibrosis, filling pressure and clinical outcomes in advanced heart failure (HF) patients before and after heart transplantation (HT).I demonstrated that HT recipients had impaired LV twist dynamics in the form of reduced rotation twist angle and untwist rate but time to peak twist was not different from the age matched controls and other cardiac surgical patients. LÄS MER

3. 2. Insights into left atrial response to pressure and volume overload

   Författare :Matteo Lisi; Michael Henein; Sergio Mondillo; Lars-Åke Lars; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keywords Mitral regurgitation; aortic stenosis; speckle tracking echocardiography; heart transplantation; left atrial strain; left ventricualr function; right ventricular function; myocardial fibrosis;

   Sammanfattning : The general purpose of this thesis is to establish the ability of Speckle Tracking Echocardiography (STE) in assessing left atrial (LA) response to pressure and volume overload respectively in aortic stenosis (AS) and mitral regurgitation (MR), and to evaluate its accuracy in predicting LA and right ventricular (RV) fibrosis in patients with end-stage heart failure (HF) undergoing heart transplantation (HTx).I demonstrated that assessment of left ventricular (LV) long axis systolic velocity and amplitude of excursion is more sensitive than simple determination of ejection fraction (EF) for revealing the beneficial impact of MR surgery on overall LV systolic performance. LÄS MER

4. 3. Diastolic heart function in hypertension-induced left ventricular hypertrophy

   Författare :Richard Müller-Brunotte; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Hypertension; left ventricular hypertrophy; diastolic function; myocardial fibrosis; angiotensin II; echocardiography;

   Sammanfattning : Hypertensive left ventricular (LV) hypertrophy is an independent strong risk factor for cardiovascular morbidity and mortality. An abnormal diastolic relaxation in the absence of systolic impairment is often seen in patients with hypertension, whether LV hypertrophy is present or not. LÄS MER

5. 4. Biomarkers of fibrosis in heart failure and relations to left ventricular size, function and outcome

   Författare :Johan Löfsjögård; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Heart failure (HF) is a syndrome with impaired quality of life and higher mortality than most forms of cancer. The excessive accumulation of collagen in the myocardial extracellular matrix is called myocardial fibrosis, which is a reaction to myocardial stress, myocardial injury and a part of the remodeling process that alters the shape, size, and function of the heart. LÄS MER

7. 5. Assessment of myocardial viability using magnetic resonance imaging

   Författare :Robert Jablonowski; Lund Klinisk fysiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Magnetic resonance imaging; myocardial infarction; hypertrophic cardiomyopathy; fibrosis; viability;

   Sammanfattning : Myocardial infarction (MI) following an acute coronary occlusion is a leading cause of morbidity and mortality. During revascularization, microemboli may complicate treatment and affect cardiac function. The long-term effects of microembolization are not fully elucidated. LÄS MER