Sökning: "large T antigen"
Visar resultat 1 - 5 av 99 avhandlingar innehållade orden large T antigen.
1. Mouse polyomavirus large T-antigen : DNA-binding and related activities
Sammanfattning : .... LÄS MER
2. DNA and protein interactions of mouse polyomavirus large T antigen
Sammanfattning : Polyomaviruses require dividing cells to multiply. The regulatory genes express proteins, theT-antigens, necessary for this to occur. Large T-antigen (LT), is a phosphoprotein withmultiple intrinsic activities, e.g. LÄS MER
3. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells
Sammanfattning : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. LÄS MER
4. T-cell regulation of immune responses to the Plasmodium falciparum antigen Pf155/RESA
Sammanfattning : Plasmodium falciparum is the cause of the most severe malaria inhumans. Due to the rapid resurgence of malaria in many parts of theworld extensive efforts have been made during the last few years todefine several P.falciparum antigens for inclusion in a vaccine. LÄS MER
5. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa
Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER