Sökning: "DNA-binding"

Visar resultat 1 - 5 av 274 avhandlingar innehållade ordet DNA-binding.

  1. 1. The adenovirus DNA-binding protein : structure and function

    Författare :Tommy Linné; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  3. 2. Mouse polyomavirus large T-antigen : DNA-binding and related activities

    Författare :Kåre Bondeson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Characterization of the DNA-Binding Properties of the Cyanobacterial Transcription Factor NtcA

    Författare :Susanne Wisén; Bengt Mannervik; Enrique Flores; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; NtcA; transcription regulation; cyanobacteria; redox regulation; DNA binding; nitrogen fixation; Anabaena PCC 7120; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : Nitrogen is an essential building block of proteins and nucleic acids and, therefore, crucial for the biosphere. Nearly 79 % of the air consists of nitrogen, but in the form of nitrogen gas (N2), which cannot be utilized by most organisms. LÄS MER

  5. 4. Structural Studies of Flexible Biomolecules and a DNA-binding Protein

    Författare :Tariq Massad; Pål Stenmark; Cheryl Arrowsmith; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Maximum entropy; motilin; DNA-binding proteins; Karplus equation; disaccaride; direct repeats; Structural biology; Strukturbiologi; Biophysics; biofysik;

    Sammanfattning : The knowledge of the three-dimensional structures of proteins and polypeptides is essential to understand their functions. The work shown in this thesis has two objectives. LÄS MER

  7. 5. Exploring new strategies of controlling DNA binding

    Författare :Johanna Andersson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Abstract Due to the increasing knowledge about DNA structure and function, as well as the fact that the sequence of the human genome is now known, DNA becomes more and more interesting as a drug target, especially for treatment of genetic diseases and cancer, but also for treatment of diseases caused by pathogens. However, one of the major challenges is to achieve specificity - in the case of genetic diseases to uniquely target a specific gene and in the case of the cancer and pathogens to target specific cells. LÄS MER