Sökning: "hydrolase"

Visar resultat 1 - 5 av 152 avhandlingar innehållade ordet hydrolase.

  1. 1. Microsomal epoxide hydrolase : characterization, induction, and in vitro modulation, of the catalytic activity

    Författare :Janeric Seidegård; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Microsomal epoxide hydrolase has been characterized, mainly in the fiver and lung of the rat.A reported radiometric assay using 3H-styrene 7,8-oxide as substrate has been modified by purifying the substrate before use, decreasing the incubation volume, and prolonging the incubation time. LÄS MER

  3. 2. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

    Författare :Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

    Sammanfattning : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. LÄS MER

  4. 3. Cytosolic epoxide hydrolase in murine liver : purification, characterization, regulation, species distribution and comparison to microsomal epoxide hydrolase

    Författare :Johan Meijer; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Biochemical Studies on a Plant Epoxide Hydrolase : Discovery of a Proton Entry and Exit Pathway and the Use of In vitro Evolution to Shift Enantioselectivity

    Författare :Ann Gurell; Mikael Widersten; Bengt Mannervik; Dick Janssen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; epoxide hydrolase; enantioselectivity; in vitro evolution; proton wire; epoxides; selectivity; CASTing; structure-function; Biochemistry; Biokemi; Biokemi; Biochemistry;

    Sammanfattning : The work leading to this thesis has provided additional information and novel knowledge concerning structure-function relationship in the potato epoxide hydrolase. Epoxide hydrolases are enzymes catalyzing the hydrolysis of epoxides to yield the corresponding vicinal diols. LÄS MER

  7. 5. Exploring glycoside hydrolase family 5 (GH5) enzymes

    Författare :Yang Wang; Ines Ezcurra; Henrik Aspeborg; Henrik Stålbrand; Torkel Berglund; KTH; []
    Nyckelord :GH5; glycoside hydrolase; subfamily classification; mannans; polysaccharides; mannanases; cell wall; GH5; glykosidhydrolas; subfamiljklassificering; mannaner; polysackarider; mannanaser; cellvägg; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : In 1990, the classification of carbohydrate-active enzymes (CAZymes) was introduced by the scientist Bernard Henrissat. According to sequence similarity, these enzymes were separated into families with conserved structures and reaction mechanisms. LÄS MER