Sökning: "human stem cells"

Visar resultat 1 - 5 av 482 avhandlingar innehållade orden human stem cells.

1. 1. Human embryonic stem cells for bone engineering applications

   Författare :Giuseppe Maria de Peppo; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human skeleton; bone; bone defects; bone regeneration; regenerative medicine; tissue engineering; biomaterials; scaffold; biocoral; titanium; osseointegration bioreactor; human stem cells; embryonic stem cells; mesenchymal stem cells; embryonic-derived progenitors; osteogenic differentiation; mineralization; immune response; in vitro; in vivo;

   Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER

3. 2. Generation of Dopaminergic Neurons from Human Embryonic Stem Cells

   Författare :Tandis Vazin; Joakim Lundeberg; Ernest Arenas; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human; dopaminergic; embryonic stem cells; differentiation; stromal cells; PA6 cells; dopamine; neurons; Neuroscience; Neurovetenskap; Neurobiology; Neurobiologi; Molecular neurobiology; Molekylär neurobiologi;

   Sammanfattning : Since the first successful derivation of human embryonic stem cells (hESC), rapid progress has been attained in the development of strategies in differentiation of these cells into various neural lineages, with the fundamental objective of using these cells for replacement and repair of damaged neuronal circuits in the central nervous system (CNS). Of particular interest are midbrain dopaminergic (mDA) neurons, which play a central role in regulation of voluntary movement. LÄS MER

4. 3. Satellite cells in human skeletal muscle : molecular identification quantification and function

   Författare :Mona Lindström; Lars-Eric Thornell; Hannu Kalimo; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; satellite cell markers; NCAM; Pax7; MyoD; myogenin; DLK1 FA1; c-Met; human skeletal muscle; immunohistochemistry; muscle growth; muscle hypertrophy; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; anatomi; Human Anatomy;

   Sammanfattning : Skeletal muscle satellite cells located between the plasma membrane and the basal lamina of muscle fibres, could for many years, only be studied in situ by electron microscopy. The introduction of immunohistochemistry and the discovery of molecular markers of satellite cells then made them accessible for light microscopic studies and a wealth of information is today available. LÄS MER

5. 4. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells

   Författare :Roger Rönn; Avdelningen för molekylärmedicin och genterapi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hematopoietic stem cells; pluripotent stem cells; embryonic development.; in vitro differentiation;

   Sammanfattning : There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. LÄS MER

7. 5. Derivation, propagation and differentiation of human stem and progenitor cells

   Författare :Mathilda Zetterström Axell; Göteborgs universitet; []
   Nyckelord :Human embryonic stem cells; neural progenitor cells; stem cells; differentiation; propagation; migration; cell culturing; rostral migratory stream; electrospun scaffolds;

   Sammanfattning : Neuronal loss is a common feature of many neurological disorders, including stroke, Parkinson’s disease, Alzheimer’s disease and traumatic brain injury. Human embryonic stem cells (hESCs) and hESC-derived neural progenitors (NPs) may provide a number of new ways for studying and treating diseases and injuries in the brain. LÄS MER